POU4F3 Is Necessary for Normal Merkel Cell Formation, whereas POU4F1 Is Dispensable.
作者信息
Jarvis Jordan E, Miao Lingling, Hallaert Patrick, Martin Mackenzie R, Collado Loren, Hill Natasha T, Brownell Isaac
机构信息
Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Dermatology Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.
出版信息
J Invest Dermatol. 2025 Jan;145(1):193-196.e5. doi: 10.1016/j.jid.2024.06.1284. Epub 2024 Jul 14.
Abstract
摘要
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本文引用的文献
1
POU4F3 pioneer activity enables ATOH1 to drive diverse mechanoreceptor differentiation through a feed-forward epigenetic mechanism.POU4F3 启动子活性通过前馈表观遗传机制使 ATOH1 驱动多种机械感受器分化。
Proc Natl Acad Sci U S A. 2021 Jul 20;118(29). doi: 10.1073/pnas.2105137118.
2
Pou4f1 Defines a Subgroup of Type I Spiral Ganglion Neurons and Is Necessary for Normal Inner Hair Cell Presynaptic Ca Signaling.Pou4f1 定义了 I 型螺旋神经节神经元的一个亚群，对于正常内毛细胞突触前 Ca 信号传导是必需的。
J Neurosci. 2019 Jul 3;39(27):5284-5298. doi: 10.1523/JNEUROSCI.2728-18.2019. Epub 2019 May 13.
3
Merkel Cells Activate Sensory Neural Pathways through Adrenergic Synapses.默克尔细胞通过肾上腺素能突触激活感觉神经通路。
Neuron. 2018 Dec 19;100(6):1401-1413.e6. doi: 10.1016/j.neuron.2018.10.034. Epub 2018 Nov 8.
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Neural Hedgehog signaling maintains stem cell renewal in the sensory touch dome epithelium.神经刺猬信号通路维持感觉触觉穹窿上皮中的干细胞更新。
Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7195-200. doi: 10.1073/pnas.1504177112. Epub 2015 May 26.
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Embryonic maturation of epidermal Merkel cells is controlled by a redundant transcription factor network.表皮默克尔细胞的胚胎成熟受一个冗余转录因子网络的控制。
Development. 2014 Dec;141(24):4690-6. doi: 10.1242/dev.112169.
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Merkel cells and touch domes: more than mechanosensory functions?默克尔细胞与触觉小体：不止于机械感觉功能？
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