Angus Zachary George, Ong Daini, Wickremasinghe Sanjeewa S
Department of Ophthalmology, Royal Victorian Eye and Ear Hospital, Melbourne, VIC, Australia.
Department of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC, Australia.
Case Rep Ophthalmol. 2024 Jul 12;15(1):548-551. doi: 10.1159/000539900. eCollection 2024 Jan-Dec.
Fluorescein angiography (FA) is a useful investigation in the diagnosis and treatment of retinal and choroidal disease. FA has well-reported adverse effects, most being mild. Very few cases have reported cutaneous venous staining following FA.
Two cases are reported. Case 1 was a 90-year-old female with bilateral neovascular age-related macular degeneration. In the few minutes following her routine FA, she developed cutaneous fluorescein staining ascending along the superficial forearm veins proximal to the cannula in situ at the dorsal wrist. Case 2 was a 50-year-old male with diabetic macular oedema. In the minutes following his FA, he developed cutaneous fluorescein staining descending along the dorsal forearm veins distal to the cannula in situ at the cubital fossa. Both patients were managed conservatively with the stain resolving in the next few days.
Cutaneous fluorescein staining around superficial vasculature is a rare phenomenon. Despite this, it seems to be self-limiting and does not require any treatment.
荧光素血管造影（FA）在视网膜和脉络膜疾病的诊断与治疗中是一项有用的检查。FA 有诸多已报道的不良反应，多数较为轻微。仅有极少数病例报道过 FA 后出现皮肤静脉染色。
报告了两例病例。病例 1 是一位 90 岁女性，患有双侧新生血管性年龄相关性黄斑变性。在她进行常规 FA 后的几分钟内，她出现了皮肤荧光素染色，沿着腕背原位插管近端的前臂浅静脉向上蔓延。病例 2 是一位 50 岁男性，患有糖尿病性黄斑水肿。在他进行 FA 后的几分钟内，他出现了皮肤荧光素染色，沿着肘窝原位插管远端的前臂背侧静脉向下蔓延。两名患者均采用保守治疗，染色在接下来的几天内消退。
浅表血管周围的皮肤荧光素染色是一种罕见现象。尽管如此，它似乎是自限性的，不需要任何治疗。
