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潜在类别增长模型在获得性免疫缺陷综合征动态防控策略中的应用进展

Application progress of latent class growth models in dynamic prevention and control strategies for acquired immunodeficiency syndrome.

作者信息

Zhai Mimi, Li Yamin, Liu Sushun, Li Yunxia, Liu Yiting, Li Li, Lei Xianyang

机构信息

Clinical Nursing Teaching and Research Section, Second Xiangya Hospital, Central South University, Changsha 410011.

Xiangya School of Nursing, Central South University, Changsha 410013.

出版信息

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2024 Apr 28;49(4):621-627. doi: 10.11817/j.issn.1672-7347.2024.230437.

Abstract

The prevention and control requirements for HIV/AIDS vary significantly among different populations, posing substantial challenges to the formulation and implementation of intervention strategies. Dynamically assessing the heterogeneity and disease progression trajectories of various groups is crucial. Latent class growth model (LCGM) serves as a statistical approach that fits a longitudinal data into N subgroups of individual development trajectories, identifying and analyzing the progression paths of different subgroups, thereby offering a novel perspective for disease control strategies. LCGM has shown significant advantages in the application of HIV/AIDS prevention and control, especially in gaining a deeper understanding and analysis of epidemiological characteristics, risk behaviors, psychological research, heterogeneity in testing, and dynamic changes. Summarizing the advantages and limitations of applying LCGM can provide a reliable basis for precise prevention and control of HIV/AIDS.

摘要

不同人群对艾滋病毒/艾滋病的防控要求差异显著,这给干预策略的制定和实施带来了巨大挑战。动态评估各类人群的异质性和疾病进展轨迹至关重要。潜在类别增长模型(LCGM)是一种统计方法,它将纵向数据拟合到个体发展轨迹的N个子组中,识别并分析不同子组的进展路径,从而为疾病控制策略提供新视角。LCGM在艾滋病毒/艾滋病防控应用中显示出显著优势,尤其在深入理解和分析流行病学特征、风险行为、心理学研究、检测异质性及动态变化方面。总结应用LCGM的优缺点可为艾滋病毒/艾滋病的精准防控提供可靠依据。

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