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机器人辅助腹腔镜根治性前列腺切除术中改良髂耻韧带悬吊后重建技术对早期控尿的影响:一项随机对照试验。

Effect of a Modified Technique of Posterior Reconstruction by Iliopectineal Ligament Suspension During Robot-assisted Laparoscopic Radical Prostatectomy on Early Continence: A Randomised Controlled Trial.

机构信息

Division of Urology, Department of Surgery, CHU de Québec-Université Laval, Quebec City, Canada.

Division of Urology, Department of Surgery, CHU de Québec-Université Laval, Quebec City, Canada.

出版信息

Urology. 2024 Nov;193:116-122. doi: 10.1016/j.urology.2024.07.028. Epub 2024 Jul 21.

Abstract

OBJECTIVE

To evaluate the effect of a modified technique of posterior reconstruction by iliopectineal ligament suspension during robot-assisted radical prostatectomy (RARP) on recovery of early continence.

METHODS

A prospective, single surgeon, single centre, randomised controlled trial was performed from August 2018 to March 2020 with 171 patients (92 control vs 79 experimental). The posterior reconstruction was done using a standard technique in the control group and was modified for the experimental group by incorporating not only the "Rocco" stitch between Denonvilliers' fascia and the rhabdosphincter but also the iliopectineal ligaments bilaterally to further improve posterior support with this suspensory 'hammock'. Both groups of patients were followed for a year with questionnaires and 24-hour pad tests.

RESULTS

Both groups were comparable in terms of baseline demographic, clinical, and pathological characteristics. With regards to recovery of urinary continence, no statistically significant differences were found for socially continent (0-1 pads per day) or fully continent (0 pads per day) rates at all time points examined (1, 3, 6, 12 months). Moreover, there were no statistically significant differences between the groups for presence of urinary symptoms, bowel symptoms, sexual function, and hormonal symptoms.

CONCLUSION

The modified technique of posterior reconstruction by iliopectineal ligament suspension is not associated with improved early continence as compared to the standard posterior reconstruction technique during RARP. Future studies may want to explore other variations of suspensory sutures that could strengthen posterior urethral support to achieve earlier recovery of continence.

摘要

目的

评估机器人辅助前列腺根治术中改良髂耻韧带悬吊带后重建技术对早期控尿恢复的影响。

方法

2018 年 8 月至 2020 年 3 月,前瞻性、单外科医生、单中心、随机对照试验纳入了 171 例患者(对照组 92 例,实验组 79 例)。对照组采用标准技术进行后重建,实验组改良技术,除了在 Denonvilliers 筋膜和横纹肌之间采用“Rocco”缝合外,还双侧采用髂耻韧带,进一步用这种悬吊“吊床”来改善后支撑。两组患者均随访 1 年,通过问卷调查和 24 小时垫试验进行随访。

结果

两组患者在基线人口统计学、临床和病理特征方面具有可比性。在尿控恢复方面,在所有检查时间点(1、3、6、12 个月),社会控尿(每天 0-1 片尿垫)或完全控尿(每天 0 片尿垫)率均无统计学差异。此外,两组在尿症状、肠症状、性功能和激素症状方面均无统计学差异。

结论

与标准后重建技术相比,机器人辅助前列腺根治术中改良髂耻韧带悬吊带后重建技术与早期控尿恢复无关。未来的研究可能需要探索其他的悬吊缝线变化,以加强后尿道的支撑,从而更早地恢复控尿。

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