Jiujiang CityKey Laboratory of Cell Therapy, Jiujiang NO.1 People's Hospital, Jiujiang, Jiangxi, 332000, China.
Department of Cardiology, Jiujiang NO.1 People's Hospital, Jiujiang, Jiangxi, 332000, China.
BMC Public Health. 2024 Jul 25;24(1):1989. doi: 10.1186/s12889-024-19558-8.
Psychological resilience has been associated with increased longevity in the oldest old; however, its significance in the broader older adult population has not been thoroughly explored. There is a lack of understanding regarding its relationship with cause-specific mortality in older adults. This study aims to address these gaps by investigating the association between psychological resilience and both overall mortality and cause-specific mortality in individuals aged 65 and older.
We enrolled 4,935 participants aged 65 and older in the Chinese Longitudinal Healthy Longevity Survey, with baseline assessments conducted in 2014 and follow-up surveys in 2018. To evaluate the associations between psychological resilience and mortality, we used Cox proportional hazards models. Additionally, we employed restricted cubic spline plots to illustrate the dose-response relationships between these variables.
During a mean (Standard Deviation) follow-up of 3.2 years (1.2), 1726 participants died. Higher psychological resilience was independently associated with lower all-cause mortality risk (Hazard ratio [HR] 0.74, 95% confidence interval [CI]: 0.67-0.82) and cause-specific mortality from cardiovascular disease (HR 0.74, 95% CI: 0.59-0.93), respiratory diseases (HR 0.63, 95% CI:0.45-0.87), and other causes (HR 0.69, 95% CI: 0.60-0.78), excluding cancer-related mortality. Similar effects were evident when examining the psychological resilience score. The dose-response analysis further indicated a gradual decrease in mortality risk corresponding to higher psychological resilience scores. Interaction analyses revealed that psychological resilience has a more pronounced effect on mortality from other causes among economically independent older adults (P-interaction = 0.02).
Enhanced psychological resilience is independently associated with reduced all-cause and some cause-specific mortality in older adults. These findings underscore the importance of addressing psychological factors in the promotion of healthy aging and longevity.
心理弹性与最年长人群的长寿有关；然而，它在更广泛的老年人群中的意义尚未得到充分探索。人们对其与老年人特定原因死亡率的关系知之甚少。本研究旨在通过调查心理弹性与 65 岁及以上个体的全因死亡率和特定原因死亡率之间的关系来解决这些差距。
我们招募了 4935 名 65 岁及以上的中国长寿纵向研究参与者，在 2014 年进行基线评估，并在 2018 年进行随访调查。为了评估心理弹性与死亡率之间的关联，我们使用了 Cox 比例风险模型。此外，我们还采用了受限立方样条图来说明这些变量之间的剂量-反应关系。
在平均（标准差）随访 3.2 年（1.2）期间，有 1726 名参与者死亡。较高的心理弹性与较低的全因死亡率风险独立相关（风险比[HR]0.74，95%置信区间[CI]：0.67-0.82），与心血管疾病（HR 0.74，95%CI：0.59-0.93）、呼吸疾病（HR 0.63，95%CI：0.45-0.87）和其他原因（HR 0.69，95%CI：0.60-0.78）的特定原因死亡率也独立相关，不包括癌症相关死亡率。当检查心理弹性评分时，也可以看到类似的效果。剂量-反应分析进一步表明，随着心理弹性评分的升高，死亡率风险逐渐降低。交互分析显示，心理弹性对经济独立的老年人其他原因死亡率的影响更为显著（P 交互=0.02）。
增强的心理弹性与老年人的全因死亡率和某些特定原因死亡率降低独立相关。这些发现强调了在促进健康老龄化和长寿方面关注心理因素的重要性。
