Sunnybrook Health Sciences Centre, Toronto, ON M4N 3M5, Canada.
Colorectal Cancer Resource & Action Network (CCRAN), Toronto, ON M4W 3E2, Canada.
Curr Oncol. 2024 Jul 19;31(7):4063-4078. doi: 10.3390/curroncol31070303.
A multi-disciplinary symposium on early-age onset cancer (EAOC) was held in October 2023 to explore challenges experienced by this rapidly growing population. A major outcome of the symposium was recognition of the remarkable similarities of EAOC patients' journeys across cancer sites. Prevention and early detection of cancer are hindered by a lack of awareness among patients and family doctors that cancer can and does occur in younger persons. Distinct characteristics of the disease-such as a later stage at diagnosis and more aggressive tumor biology-require more potent treatments, which result in profound physical and psychosocial consequences that are unique to this age group. EAOC patient empowerment emerged as another key theme of the symposium. The development of a greater number of specialized clinics was called for, and patient support groups were recognized for the vital role they play in empowering patients and their families. Leading-edge medical advancements hold tremendous hope across the spectrum of EAOC care. New technologies based on genomic profiling, immunotherapy and microbiome alteration contribute to the development of highly effective, personalized approaches to treatment. All symposium participants expressed their commitment to speak with one resounding voice to advocate for equitable access to leading care practices for EAOC patients; thus, a fourth symposium is planned for November 2024.
2023 年 10 月举办了一次多学科早期发病癌症(EAOC)研讨会,旨在探讨这一快速增长人群所面临的挑战。研讨会的一个主要成果是认识到,不同癌症部位的 EAOC 患者的治疗过程存在显著的相似之处。由于患者和家庭医生缺乏认识,认为癌症不会也不可能发生在年轻人身上,因此癌症的预防和早期发现受到阻碍。这种疾病的独特特征,如诊断时更晚期和更具侵袭性的肿瘤生物学,需要更有效的治疗方法,这会导致该年龄段特有的深刻的身体和心理社会后果。EAOC 患者赋权也成为研讨会的另一个关键主题。呼吁设立更多的专门诊所,并认识到患者支持团体在赋予患者及其家属权力方面发挥的重要作用。先进的医疗技术在 EAOC 治疗的各个方面都带来了巨大的希望。基于基因组分析、免疫疗法和微生物组改变的新技术有助于开发高度有效的个性化治疗方法。所有研讨会参与者都表示承诺以一个响亮的声音为 EAOC 患者争取公平获得领先治疗实践的机会;因此,计划于 2024 年 11 月举办第四次研讨会。