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母体饮食对婴儿健康的影响:基于肠道微生物群肠-乳腺途径的综述。

Effects of Maternal Diet on Infant Health: A Review Based on Entero-Mammary Pathway of Intestinal Microbiota.

机构信息

Key Laboratory for Food Microbial Technology of Zhejiang Province, College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou, 310018, China.

出版信息

Mol Nutr Food Res. 2024 Jul;68(14):e2400077. doi: 10.1002/mnfr.202400077. Epub 2024 Jun 22.

Abstract

SCOPE

The microbes in breast milk are critical for the early establishment of infant gut microbiota and have important implications for infant health. Breast milk microbes primarily derive from the migration of maternal intestinal microbiota. This review suggests that the regulation of maternal diet on gut microbiota may be an effective strategy to improve infant health.

METHODS AND RESULTS

This article reviews the impact of breast milk microbiota on infant development and intestinal health. The close relationship between the microbiota in the maternal gut and breast through the entero-mammary pathway is discussed. Based on the effect of diet on gut microbiota, it is proposed that changing the maternal dietary structure is a new strategy for regulating breast milk microbiota and infant intestinal microbiota, which would have a positive impact on infant health.

CONCLUSION

Breast milk microbes have beneficial effects on infant development and regulation of the immune system. The mother's gut and breast can undergo certain bacterial migration through the entero-mammary pathway. Research has shown that intervening in a mother's diet during breastfeeding can affect the composition of the mother's gut microbiota, thereby regulating the microbiota of breast milk and infant intestines, and is closely related to infant health.

摘要

范围

母乳中的微生物对于婴儿肠道微生物群的早期建立至关重要,对婴儿健康有重要影响。母乳微生物主要来源于母体肠道微生物的迁移。本综述表明,调节母体饮食对肠道微生物群可能是改善婴儿健康的有效策略。

方法和结果

本文综述了母乳微生物群对婴儿发育和肠道健康的影响。讨论了通过肠乳途径母体肠道和母乳之间的密切关系。基于饮食对肠道微生物群的影响,提出改变母体饮食结构是调节母乳微生物群和婴儿肠道微生物群的新策略,这将对婴儿健康产生积极影响。

结论

母乳微生物对婴儿发育和免疫系统调节有有益影响。母亲的肠道和乳房可以通过肠乳途径发生一定的细菌迁移。研究表明,在母乳喂养期间干预母亲的饮食可以影响母亲肠道微生物群的组成,从而调节母乳和婴儿肠道的微生物群,与婴儿健康密切相关。

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