Unraveling the influence of Pavlovian cues on decision-making: A pre-registered meta-analysis on Pavlovian-to-instrumental transfer.

Amidst the replicability crisis, promoting transparency and rigor in research becomes imperative. The Pavlovian-to-Instrumental Transfer (PIT) paradigm is increasingly used in human studies to offer insights into how Pavlovian cues, by anticipating rewards or punishments, influence decision-making and potentially contribute to the development of clinical conditions. However, research on this topic faces challenges, including methodological variability and the need for standardized approaches, which can undermine the quality and robustness of experimental findings. Hence, we conducted a meta-analysis to unravel the methodological, task-related, individual, training, and learning factors that can modulate PIT. By scrutinizing these factors, the present meta-analysis reviews the current literature on human PIT, provides practical guidelines for future research to enhance study outcomes and refine methodologies, and identifies knowledge gaps that can serve as a direction for future studies aiming to advance the comprehension of how Pavlovian cues shape decision-making.