Division of Endocrinology, Diabetes, and Metabolic Diseases, Medical University of South Carolina, 96 Jonathan Lucas Street, CSB 822, Charleston, SC 29425, USA.
Department of Medicine, Division of Endocrinology, Diabetes, and Hypertension, Brigham & Women's Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA.
Endocrinol Metab Clin North Am. 2024 Sep;53(3):377-389. doi: 10.1016/j.ecl.2024.05.012.
There have been recent advances in the prevention, diagnosis, and management of hypertensive disorders of pregnancy which complicate approximately 16% of pregnancies in the United States. Initiation of low-dose aspirin by 16 weeks' gestation reduces preeclampsia in high-risk women. The Food and Drug Administration approved the use of the soluble fms-like tyrosine kinase 1/placental growth factor ratio for the short-term prediction of preeclampsia. Pregnancy outcomes are improved in women with chronic hypertension when antihypertensives are initiated at a threshold blood pressure of 140/90 mm Hg. Women with prior preeclampsia have increased cardiovascular disease risk and should receive risk reduction counseling.
近年来,高血压疾病的预防、诊断和管理取得了进展,这种疾病在美国约占 16%的妊娠并发症。高危人群在 16 周妊娠时开始服用小剂量阿司匹林可减少子痫前期的发生。食品和药物管理局批准使用可溶性 fms 样酪氨酸激酶 1/胎盘生长因子比值来短期预测子痫前期。对于慢性高血压患者,当血压达到 140/90mmHg 时开始使用降压药,可改善妊娠结局。有子痫前期病史的女性心血管疾病风险增加,应接受风险降低咨询。