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超声引导下膝状神经阻滞治疗膝骨关节炎:病例系列

ULTRASOUND-GUIDED GENICULAR NERVE BLOCK FOR KNEE OSTEOARTHRITIS: A CASE SERIES.

作者信息

Ramalho Ramon Chaves, Fernandes Tifani Dawidowicz, Peraro Felipe de Freitas, Pugliese Gabriel Marques, Arliani Gustavo Gonçalves, Ferreira Gabriel Ferraz

机构信息

Instituto Prevent Senior, São Paulo, SP, Brazil.

出版信息

Acta Ortop Bras. 2024 Jul 26;32(3):e277781. doi: 10.1590/1413-785220243203e277781. eCollection 2024.

DOI:10.1590/1413-785220243203e277781
PMID:39086844
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11288321/
Abstract

OBJECTIVE

Knee genicular nerve blocks have been a topic of discussion among various types of treatment for knee osteoarthritis. This study aims to evaluate the pain and function of patients diagnosed with knee osteoarthritis after undergoing ultrasound-guided genicular nerve blockade using pharmacological agents.

METHODS

The study included 36 patients diagnosed with knee osteoarthritis, comprising 17 bilateral cases, totaling 53 knees undergoing UGNB using a mixture of triamcinolone, ropivacaine, and lidocaine under ultrasound guidance. Epidemiological data, pain outcomes measured by the Visual Analog Scale (VAS), and function assessed using the Western Ontario and McMaster Universities (WOMAC) score were evaluated before and after 12 weeks of the procedure.

RESULTS

The mean age was 75.5 years (standard deviation of 9.4 years), with a predominance of females and right-sided involvement. There was a mean reduction of 3.0 points in VAS (p < 0.001) and 15.4 points in WOMAC (p < 0.001). Two cases reported only minor and transient complications related to the procedure (skin anesthesia and edema).

CONCLUSION

Ultrasound-guided genicular nerve blockade using pharmacological agents demonstrated pain reduction and improved function with a low complication rate after 12 weeks in patients with knee gonarthrosis.

摘要

目的

在膝关节骨关节炎的各类治疗方法中,膝部膝状神经阻滞一直是讨论的话题。本研究旨在评估经药物超声引导下膝状神经阻滞治疗后,诊断为膝关节骨关节炎患者的疼痛和功能情况。

方法

该研究纳入了36例诊断为膝关节骨关节炎的患者,其中17例为双侧病例,共计53个膝关节在超声引导下接受了曲安奈德、罗哌卡因和利多卡因混合液的超声引导下膝状神经阻滞(UGNB)。在手术前及术后12周评估流行病学数据、采用视觉模拟评分法(VAS)测量的疼痛结果以及使用西安大略和麦克马斯特大学(WOMAC)评分评估的功能。

结果

平均年龄为75.5岁(标准差为9.4岁),女性及右侧受累者居多。VAS平均降低3.0分(p < 0.001),WOMAC平均降低15.4分(p < 0.001)。2例报告仅出现与手术相关的轻微短暂并发症(皮肤麻醉和水肿)。

结论

在膝关节病患者中,经药物超声引导下膝状神经阻滞在12周后显示出疼痛减轻、功能改善且并发症发生率低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a3d/11288321/405ea1b4407a/1809-4406-aob-32-03-e277781-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a3d/11288321/a110f3544947/1809-4406-aob-32-03-e277781-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a3d/11288321/405ea1b4407a/1809-4406-aob-32-03-e277781-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a3d/11288321/a110f3544947/1809-4406-aob-32-03-e277781-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a3d/11288321/405ea1b4407a/1809-4406-aob-32-03-e277781-f2.jpg

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本文引用的文献

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Arthritis Rheumatol. 2023 Feb;75(2):201-209. doi: 10.1002/art.42384. Epub 2022 Nov 11.
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Ultrasound-guided Genicular Nerve Blockade With Pharmacological Agents for Chronic Knee Osteoarthritis: A Systematic Review.超声引导下药物关节内神经阻滞治疗慢性膝骨关节炎的系统评价。
Pain Physician. 2022 Jul;25(4):E489-E502.
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Protocol for the Request of Knee Magnetic Resonance Imaging in Elderly Patients with Suspected Osteoarthritis: Reduction in Test Requests and Impact on Management and Diagnosis.
疑似骨关节炎老年患者膝关节磁共振成像检查申请方案:减少检查申请及对管理和诊断的影响
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Intra-articular Infiltration of Platelet-Rich Plasma versus Hyaluronic Acid in Patients with Primary Knee Osteoarthritis: Preliminary Results from a Randomized .原发性膝骨关节炎患者关节腔内注射富血小板血浆与透明质酸的比较:一项随机研究的初步结果
Rev Bras Ortop (Sao Paulo). 2021 Apr 19;57(3):402-408. doi: 10.1055/s-0041-1724082. eCollection 2022 Jun.
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