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先天性单支右冠状动脉急性心肌梗死患者经皮冠状动脉介入治疗成功:病例报告及文献复习。

Successful percutaneous coronary intervention in a congenital single right coronary artery with acute myocardial infarction: A case report and literature review.

机构信息

Department of Cardiology, The 960th Hospital of the Joint Service Support Force of the People's Liberation Army, Jinan, China.

Department of Obstetrics, The Jinan Maternity and Child Care Centers, Jinan, China.

出版信息

Medicine (Baltimore). 2024 Aug 2;103(31):e39143. doi: 10.1097/MD.0000000000039143.

Abstract

RATIONALE

Single coronary artery (SCA) is a rare coronary artery malformation. SCA combined with atherosclerotic plaques can cause severe and widespread myocardial ischemia and infarction, leading to hemodynamic instability and even sudden death.

PATIENT CONCERNS

A 48-year-old Chinese man was admitted for treatment of persistent chest tightness and panic for 5 hours. The patient was a lorry driver with high work intensity and mental stress, with body mass index of 33.78, history of smoking and alcohol consumption, but no history of hypertension and diabetes.

DIAGNOSES

Admission examination showed Troponin was 183.083 µg/L and CK-MB value was >300 µg/L. The patient was diagnosed with a congenital single right coronary artery (RCA) with acute myocardial infarction (AMI) by coronary angiography (CAG). Due to atherosclerotic plaques rupture, a complete occlusion of the proximal RCA with thrombolysis in myocardial infarction grade 0 of distal blood flow were found.

INTERVENTIONS AND OUTCOMES

The patient was treated with thrombus aspiration and thrombolytic therapy by percutaneous coronary intervention under the support of intra-aortic balloon pump. Postoperative the chest tightness and panic were relieved, and CAG revealed that the proximal thrombus of the RCA was reduced, and distal blood flow was restored to thrombolysis in myocardial infarction grade 3. After 2 weeks of intensive antithrombotic and lipid-regulating drug therapy, the patient was successfully discharged. Follow-up for 6 months, the patient was able to live and work normally without experiencing chest tightness and chest pain. Computed tomography angiography (CTA) confirmed a congenital single RCA with patent lumen and no severe stenosis.

LESSONS

The congenital single RCA is very rare, and it is fatal in conjunction with acute coronary syndrome. Early detection and appropriate treatment is critical for AMI patient with single RCA. CAG is the gold standard for diagnosis of single RCA, and CTA is a necessary to describe the anatomical course of abnormal coronary arteries.

摘要

背景

单支冠状动脉(SCA)是一种罕见的冠状动脉畸形。SCA 合并粥样硬化斑块可导致严重且广泛的心肌缺血和梗死,引起血流动力学不稳定甚至猝死。

病例介绍

一名 48 岁的中国男性因持续 5 小时胸闷、恐慌而入院治疗。患者为卡车司机,工作强度大,精神压力大,体质指数为 33.78,有吸烟和饮酒史,但无高血压和糖尿病病史。入院检查示肌钙蛋白 183.083µg/L,肌酸激酶同工酶>300µg/L。冠状动脉造影(CAG)诊断为先天性单支右冠状动脉(RCA)合并急性心肌梗死(AMI)。由于粥样硬化斑块破裂,RCA 近端完全闭塞,血流为心肌梗死溶栓治疗(TIMI)0 级。

干预措施和结果

患者在主动脉内球囊反搏支持下行经皮冠状动脉介入治疗,行血栓抽吸和溶栓治疗。术后胸闷、恐慌缓解,CAG 显示 RCA 近端血栓减少,远端血流恢复至 TIMI 3 级。术后 2 周给予强化抗栓、调脂药物治疗后,患者成功出院。随访 6 个月,患者能正常生活和工作,无胸闷、胸痛。计算机断层血管造影(CTA)证实先天性单支 RCA,管腔通畅,无严重狭窄。

结论

先天性单支 RCA 非常罕见,与急性冠状动脉综合征并存时可致命。早期发现和适当治疗对单支 RCA 的 AMI 患者至关重要。CAG 是诊断单支 RCA 的金标准,CTA 是描述异常冠状动脉解剖的必要手段。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f68/11296457/7b27ef35c349/medi-103-e39143-g001.jpg

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