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超声引导下喉上神经阻滞:旁矢状位与横位入路的随机比较。

Ultrasound-guided superior laryngeal nerve block: a randomized comparison between parasagittal and transverse approach.

机构信息

Department of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu Province, 210006, China.

Department of Anesthesiology, The Second affiliated hospital of Nanjing, University of Chinese Medicine, Nanjing, 210004, China.

出版信息

BMC Anesthesiol. 2024 Aug 3;24(1):269. doi: 10.1186/s12871-024-02612-8.

Abstract

BACKGROUND

Different approach ultrasound-guided superior laryngeal nerve block was used to aid awake intubation, but little is known which approach was superior. We aimed to compare the parasagittal and transverse approaches for ultrasound-guided superior laryngeal nerve block in adult patients undergoing awake intubation.

METHODS

Fifty patients with awake orotracheal intubation were randomized to receive either a parasagittal or transverse ultrasound-guided superior laryngeal nerve block. The primary outcome was patient's quality of airway anesthesia grade during insertion of the tube into the trachea. The patients' tube tolerance score after intubation, total procedure time, mean arterial pressure, heart rate, Ramsay sedation score at each time point, incidence of sore throat both 1 h and 24 h after extubation, and hoarseness before intubation, 1 h and 24 h after extubation were documented.

RESULTS

Patients' quality of airway anesthesia was significantly better in the parasagittal group than in the transverse group (median grade[IQR], 0 [0-1] vs. 1 [0-1], P = 0.036). Patients in the parasagittal approach group had better tube tolerance scores (median score [IQR],1[1-1] vs. 1 [1-1.5], P = 0.042) and shorter total procedure time (median time [IQR], 113 s [98.5-125.5] vs. 188 s [149.5-260], P < 0.001) than those in the transverse approach group. The incidence of sore throat 24 h after extubation was lower in the parasagittal group (8% vs. 36%, P = 0.041). Hoarseness occurred in more than half of the patients in parasagittal group before intubation (72% vs. 40%, P = 0.023).

CONCLUSIONS

Compared to the transverse approach, the ultrasound-guided parasagittal approach showed improved efficacy in terms of the quality of airway topical anesthesia and shorter total procedure time for superior laryngeal nerve block.

TRIAL REGISTRATION

This prospective, randomized controlled trial was approved by the Ethics Committee of Nanjing First Hospital (KY20220425-014) and registered in the Chinese Clinical Trial Registry (19/6/2022, ChiCTR2200061287) prior to patient enrollment. Written informed consent was obtained from all participants in this trial.

摘要

背景

不同的超声引导喉上神经阻滞方法被用于辅助清醒插管,但哪种方法更优尚不清楚。我们旨在比较成人清醒经口气管插管中使用的旁正中入路和横切入路超声引导喉上神经阻滞的效果。

方法

50 例清醒或经口气管插管患者被随机分为接受旁正中入路或横切入路超声引导喉上神经阻滞。主要结局为管插入气管时患者气道麻醉的质量。记录患者插管后的管耐受评分、总操作时间、平均动脉压、心率、每个时间点的 Ramsay 镇静评分、插管后 1 小时和 24 小时咽痛的发生率、插管前、插管后 1 小时和 24 小时声音嘶哑的发生率。

结果

旁正中组患者的气道麻醉质量明显优于横切组(中位数[IQR],0 [0-1] vs. 1 [0-1],P=0.036)。旁正中组的患者管耐受评分更好(中位数评分[IQR],1[1-1] vs. 1 [1-1.5],P=0.042),总操作时间更短(中位数时间[IQR],113 s [98.5-125.5] vs. 188 s [149.5-260],P<0.001)。旁正中组患者插管后 24 小时咽痛的发生率较低(8% vs. 36%,P=0.041)。旁正中组患者在插管前声音嘶哑的发生率超过一半(72% vs. 40%,P=0.023)。

结论

与横切入路相比,超声引导旁正中入路在喉上神经阻滞的气道局部麻醉质量和总操作时间方面显示出更好的效果。

试验注册

这项前瞻性、随机对照试验获得了南京第一医院伦理委员会的批准(KY20220425-014),并在患者入组前在中国临床试验注册中心(19/6/2022,ChiCTR2200061287)注册。本试验中的所有参与者均签署了书面知情同意书。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b45e/11297642/cbe5ffeb508c/12871_2024_2612_Fig1_HTML.jpg

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