Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Neurology and Intracranial Hypertension and Cerebral Venous Disease Center, National Health Commission of China, Xuanwu Hospital, Capital Medical University, Beijing, China.
CNS Neurosci Ther. 2024 Aug;30(8):e14895. doi: 10.1111/cns.14895.
Idiopathic intracranial hypertension (IIH) mainly affects obese young women, causing elevated intracranial pressure, headaches, and papilledema, risking vision loss and severe headaches. Despite weight loss as the primary treatment, the underlying mechanisms remain unclear. Recent research explores novel therapeutic targets.
This review aimed to provide a comprehensive understanding of IIH's pathophysiology and clinical features to inform pathogenesis and improve treatment strategies.
Recent publications on IIH were searched and summarized using PubMed, Web of Science, and MEDLINE.
The review highlights potential pathomechanisms and therapeutic advances in IIH.
IIH incidence is rising, with growing evidence linking it to metabolic and hormonal disturbances. Early diagnosis and treatment remain challenging.
特发性颅内高压（IIH）主要影响肥胖的年轻女性，导致颅内压升高、头痛和视盘水肿，有视力丧失和严重头痛的风险。尽管减肥是主要的治疗方法，但潜在的机制仍不清楚。最近的研究探索了新的治疗靶点。
本综述旨在全面了解 IIH 的病理生理学和临床特征，以了解发病机制并改善治疗策略。
使用 PubMed、Web of Science 和 MEDLINE 搜索并总结了关于 IIH 的最新出版物。
该综述强调了 IIH 的潜在发病机制和治疗进展。
IIH 的发病率正在上升，越来越多的证据表明其与代谢和激素紊乱有关。早期诊断和治疗仍然具有挑战性。
