Division of Pulmonary and Critical Care Medicine, University of Florida - Jacksonville, Jacksonville, Florida.
Department of Dermatology, Mayo Clinic Florida, Jacksonville, Florida.
Transplant Proc. 2024 Jul-Aug;56(6):1454-1456. doi: 10.1016/j.transproceed.2024.05.023. Epub 2024 Aug 3.
Chromoblastomycosis (CBM), also known as chromomycosis is a chronic, granulomatous fungal infection of the skin and subcutaneous tissue. It usually occurs by the traumatic inoculation of various dematiaceous fungi and is more common in the developing world. This condition is rare in North America and the developed world. Herein, we present a case of a 75-year-old man who received a bilateral lung transplant 4 months prior and presented for evaluation of a painful, erythematous papule on the elbow which was diagnosed as CBM. This case highlights that immunosuppression used in patients who undergo solid organ transplantation not only increases the risk of opportunistic infections like CBM but can also be confused for cutaneous squamous cell carcinoma as both these entities share many overlapping clinical and histopathologic features and may be a potential source of misdiagnosis.
着色芽生菌病(CBM),也称为暗色丝孢霉病,是一种慢性、肉芽肿性皮肤和皮下组织真菌感染。它通常通过各种暗色真菌的创伤性接种而发生,在发展中国家更为常见。这种情况在北美和发达国家很少见。在此,我们介绍了一例 75 岁男性,他在 4 个月前接受了双侧肺移植,并因肘部出现疼痛性红斑丘疹就诊,被诊断为 CBM。该病例提示,接受实体器官移植的患者使用的免疫抑制不仅会增加 CBM 等机会性感染的风险,还可能与皮肤鳞状细胞癌相混淆,因为这两种疾病具有许多重叠的临床和组织病理学特征,并且可能是误诊的潜在来源。