DKMS Group gGmbH, Clinical Trials Unit, Dresden, Germany.
DKMS Group gGmbH, Tübingen, Germany.
Best Pract Res Clin Haematol. 2024 Jun;37(2):101551. doi: 10.1016/j.beha.2024.101551. Epub 2024 Apr 1.
Biobanking provides benefit for future generations by facilitating medical research and subsequent translation and application of research findings. Long-term storage and research involving biological material and associated data necessitate the proper implementation of ethical and legal standards. A key principle includes recognizing informed consent as a crucial element for legitimizing the collection of biological material and data. Furthermore, any collected material and data must be employed exclusively for the research framework that aligns with the explicit consent provided by the participants. Last but not least, data privacy and security are essential in biobanking. This review elucidates chances and limitations of biobanking in the field of allogeneic hematopoietic cell transplantation. We discuss the practical implementation of the requirements, illustrated by the Collaborative Biobank, a collaborative research platform for research in blood cancer.
生物库通过促进医学研究以及随后的研究成果转化和应用,为后代带来益处。长期储存和涉及生物材料及相关数据的研究需要正确实施伦理和法律标准。一个关键原则包括承认知情同意是使生物材料和数据收集合法化的关键要素。此外,任何收集的材料和数据必须专门用于与参与者明确同意一致的研究框架。最后但同样重要的是,生物库中的数据隐私和安全至关重要。本综述阐明了同种异体造血细胞移植领域生物库的机遇和局限性。我们通过协作生物库(一个血液癌研究的协作研究平台)讨论了要求的实际实施情况。