婴儿巨细胞病毒唾液和尿液检测在先天性感染检测中的一致性
Concordance of Cytomegalovirus Saliva and Urine Testing in Infants for the Detection of Congenital Infection.
作者信息
Stark Ashley, Greenberg Rachel G, Pittman Rick, Weimer Kristin E D
机构信息
From the Department of Pediatrics, Duke University Medical Center.
Duke Clinical Research Institute, Durham, North Carolina.
出版信息
Pediatr Infect Dis J. 2024 Dec 1;43(12):1191-1193. doi: 10.1097/INF.0000000000004492. Epub 2024 Aug 2.
Congenital cytomegalovirus is a leading cause of neurodevelopmental impairment and sensorineural hearing loss. We evaluated infants ≤21 days postnatal age who had both urine and saliva cytomegalovirus testing and determined concordance between the 2 tests and influence of very low birth weight on concordance. Discordance was low overall between urine and saliva testing; however, discordance was high in very low birth weight infants.
先天性巨细胞病毒是神经发育障碍和感音神经性听力损失的主要原因。我们评估了出生后年龄≤21天、同时进行尿液和唾液巨细胞病毒检测的婴儿，并确定了两种检测结果之间的一致性以及极低出生体重对一致性的影响。尿液检测和唾液检测之间的总体不一致率较低；然而，极低出生体重婴儿的不一致率较高。
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