Droz J P, Cukier J, Beurton D, Terdjman S, Théodore C, Amiel J L
J Urol (Paris). 1985;91(7):435-40.
From January 1981 until December 1983, 51 patients have been submitted to total cystectomy for infiltrative bladder cancer, stages B2 C and D1 of the Marshall classification. They have be proposed in a trial of feasibility with adjuvant chemotherapy using Adriamycin and Cis Platinum. 24 patients have been excluded, 17 because medical contraindications, 5 because they were foreigners, 3 because they refused the therapy. 27 patients have received the chemotherapy. In 5 patients the treatment has been interrupted before the completion of 6 cycles. The results show the feasibility of a trial with adjuvant chemotherapy. The theorical rationale and the methodology are discussed.
从1981年1月至1983年12月,51例浸润性膀胱癌患者接受了全膀胱切除术,根据马歇尔分类法,这些患者处于B2、C和D1期。他们被纳入一项使用阿霉素和顺铂进行辅助化疗的可行性试验。24例患者被排除,17例是因为医学禁忌,5例是因为他们是外国人,3例是因为拒绝治疗。27例患者接受了化疗。5例患者在完成6个周期之前中断了治疗。结果显示辅助化疗试验是可行的。本文讨论了理论依据和方法。