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COVID-19 患者肺部毛霉菌病表现:病例系列。

Pulmonary mucormycosis as a presentation of COVID 19: Case series.

机构信息

Department of Radiodiagnosis, All India Institute of Medical Sciences, Bathinda, Punjab, India.

Department of General Medicine, All India Institute of Medical Sciences, Bathinda, Punjab, India.

出版信息

Indian J Tuberc. 2024 Jul;71(3):366-369. doi: 10.1016/j.ijtb.2024.02.002. Epub 2024 Feb 20.

Abstract

BACKGROUND

Pulmonary Mucormycosis (PM) is a relatively uncommon fungal disease, usually manifested in immunocompromised patients. It has an aggressive course, along with dilemmas in diagnosis and treatment. In view of the surge of Mucormycosis patients in COVID 19 pandemic, clinicians need to consider PM in suspected cases, and act in an expedited manner to avoid misdiagnosis and initiate prompt treatment.

CASE PRESENTATION

In this case series, we present four cases of PM with varied presentation, clinical course and discuss management strategies.

CONCLUSIONS

A strong suspicion of PM based on epidemiological and clinical findings should be considered, to ensure appropriate and timely treatment. It should be accompanied by judicious use of corticosteroids and aggressive control of comorbid conditions to decrease preventable morbidity and mortality.

摘要

背景

肺毛霉菌病(PM)是一种相对少见的真菌感染病,通常发生在免疫功能低下的患者中。其病程具有侵袭性,在诊断和治疗方面存在诸多困境。鉴于 COVID-19 大流行期间毛霉菌病患者数量的激增,临床医生需要在疑似病例中考虑 PM,并迅速采取行动,以避免误诊并及时启动治疗。

病例介绍

在本病例系列中,我们介绍了 4 例具有不同表现、临床病程的 PM 病例,并讨论了管理策略。

结论

应根据流行病学和临床发现强烈怀疑 PM,以确保获得适当和及时的治疗。同时,应谨慎使用皮质类固醇,并积极控制合并症,以降低可预防的发病率和死亡率。

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