活血祛风汤联合通关液化穴位渗透疗法对缺血性脑卒中患者吞咽功能及生活质量的影响
Effects of Huoxue Qufeng Decoction combined with Tongguan Liquefying Acupoint Penetration therapy on swallowing function and quality of life in patients with ischemic stroke.
作者信息
Liang Xuzhong, Ma Li, Zhang Lixia, Yang Dongnian, Zeng Lanrui
机构信息
Department of Pharmacy, Dingxi People's Hospital No. 22 Anding Road, Anding District, Dingxi 743000, Gansu, China.
Department of Cardiovascular II, The First People's Hospital of Lanzhou City No. 1 Wujiayuan West Street, Qilihe District, Lanzhou 730050, Gansu, China.
出版信息
Am J Transl Res. 2024 Jul 15;16(7):3046-3054. doi: 10.62347/WWYP7009. eCollection 2024.
OBJECTIVE
To analyze the effects of Huoxue Qufeng Decoction combined with Tongguan Liquefying Acupoint Penetration therapy on swallowing function and quality of life in patients with ischemic stroke.
METHODS
A total of 145 patients with post-stroke dysphagia admitted to Dingxi People's Hospital from January 2019 to May 2022 were selected with 65 patients in the control group and 80 patients in the observation group. The control group received Huoxue Qufeng Decoction alone, while the observation group received additional Tongguan Liquefying Acupoint Penetration therapy. Clinical efficacy, NIH Stroke Scale (NIHSS) score, Water Swallow Test, Swallowing Function Assessment (SSA) score, MD Anderson Dysphagia Inventory (MDADI) score, overall incidence of adverse events, and Swallowing Quality of Life (SWAL-QOL) score were compared between the two groups.
RESULTS
The total response rate in the observation group was higher than that in the control group, with a statistically significant difference (P<0.01). After treatment, the SSA score and NIHSS score were statistically lower in the observation group than in the control group (P<0.01). The MDADI and SWAL-QOL scores were higher in the observation group than in the control group, with a statistically significant difference (both P<0.01). The total effective rate reflected by the Water Swallow Test was significantly higher in the observation group than in the control group (P<0.05). There was no significant difference in the incidence of adverse events between the two groups (P>0.05). Univariate analysis revealed that age and treatment plan were factors influencing the recovery of swallowing function. Logistic multivariate regression analysis further identified age and treatment plan as independent risk factors affecting patient prognosis (P<0.05).
CONCLUSION
Huoxue Qufeng Decoction combined with Tongguan Liquefying Acupoint Penetration has a significant effect on post-stroke dysphagia, effectively improving swallowing function and enhancing quality of life.
目的
分析活血祛风汤联合通关液化穴位渗透疗法对缺血性脑卒中患者吞咽功能及生活质量的影响。
方法
选取2019年1月至2022年5月在定西市人民医院住院的145例脑卒中后吞咽障碍患者，将65例患者作为对照组，80例患者作为观察组。对照组单纯给予活血祛风汤治疗，观察组在对照组基础上联合通关液化穴位渗透疗法。比较两组的临床疗效、美国国立卫生院卒中量表（NIHSS）评分、饮水试验、吞咽功能评估（SSA）评分、MD安德森吞咽障碍量表（MDADI）评分、不良事件总发生率及吞咽生活质量（SWAL-QOL）评分。
结果
观察组总有效率高于对照组，差异有统计学意义（P<0.01）。治疗后，观察组SSA评分及NIHSS评分低于对照组，差异有统计学意义（P<0.01）。观察组MDADI评分及SWAL-QOL评分高于对照组，差异有统计学意义（均P<0.01）。饮水试验反映的总有效率观察组明显高于对照组（P<0.05）。两组不良事件发生率比较，差异无统计学意义（P>0.05）。单因素分析显示年龄和治疗方案是影响吞咽功能恢复的因素。Logistic多因素回归分析进一步确定年龄和治疗方案是影响患者预后的独立危险因素（P<0.05）。
结论
活血祛风汤联合通关液化穴位渗透疗法对脑卒中后吞咽障碍有显著疗效，能有效改善吞咽功能，提高生活质量。
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