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巴西东北部 HIV 感染者焦虑和抑郁症状的相关因素。

Factors Associated With Symptoms of Anxiety and Depression in People Living With HIV in Northeast Brazil.

机构信息

Department of Nursing, Federal University of Ceará, Fortaleza, Ceará, Brazil.

Drug Research and Development Center, Federal University of Ceará, Fortaleza, Ceará, Brazil; and.

出版信息

J Acquir Immune Defic Syndr. 2024 Sep 1;97(1):87-98. doi: 10.1097/QAI.0000000000003468.

Abstract

BACKGROUND

The diagnosis of HIV infection can cause mental disorders or exacerbate existing symptoms because of the stigma, psychological stress, and need for the self-management of the illness. The aim of this study was to determine the prevalence of anxiety and depression symptoms in people with HIV and to identify the associated factors.

METHODS

This is a cross-sectional study. A sample of 385 people living with HIV (PLWH) was interviewed using the Sociodemographic, Epidemiological, and Clinical Form; the Beck Anxiety Inventory; the Beck Depression Inventory; and Pittsburgh Sleep Quality Index. Univariate and multivariate logistic regression analysis were performed. The odds ratio and 95% confidence interval were calculated.

RESULTS

The prevalence of anxiety was 27.1% and depression was 39.8%. Being female (P = 0.0227), antiretroviral therapy (ART) for 8 years or less (P = 0.0042), and having depression (P < 0.0001) were associated with the occurrence of anxiety. Having a detectable viral load (P = 0.0476), not exercising regularly (P = 0.0070), and having sleep disorders (P = 0.0001) and anxiety (P < 0.0001) were associated with depression. Retired and on leave or sick pay were, respectively, 2.67 and 3.90 times more likely to have depression than those who were employed.

CONCLUSIONS

A considerable percentage of PLWH have anxiety and depression symptoms. Being female, less than 8 years of ART, and depression are associated with anxiety, while detectable viral load, not practicing physical exercise, having sleep disorders, anxiety, and being retired or on leave or sick pay are associated with depression. The study showed important data for health interventions by members of the multidisciplinary team for PLWH.

摘要

背景

艾滋病病毒感染的诊断可能会导致精神障碍或使现有症状恶化,原因是污名化、心理压力和对疾病自我管理的需要。本研究的目的是确定艾滋病毒感染者中焦虑和抑郁症状的患病率,并确定相关因素。

方法

这是一项横断面研究。使用社会人口学、流行病学和临床表、贝克焦虑量表、贝克抑郁量表和匹兹堡睡眠质量指数对 385 名艾滋病毒感染者(PLWH)进行了访谈。进行了单变量和多变量逻辑回归分析。计算了比值比和 95%置信区间。

结果

焦虑的患病率为 27.1%,抑郁的患病率为 39.8%。女性(P=0.0227)、接受抗逆转录病毒治疗(ART)不足 8 年(P=0.0042)和患有抑郁(P<0.0001)与焦虑的发生相关。病毒载量可检测(P=0.0476)、不规律锻炼(P=0.0070)、睡眠障碍(P=0.0001)和焦虑(P<0.0001)与抑郁相关。退休或病假或病假与就业相比,抑郁的可能性分别为 2.67 倍和 3.90 倍。

结论

相当一部分 PLWH 存在焦虑和抑郁症状。女性、ART 不足 8 年和抑郁与焦虑相关,而病毒载量可检测、不进行体育锻炼、存在睡眠障碍、焦虑和退休或病假或病假与抑郁相关。该研究为多学科团队为 PLWH 提供健康干预提供了重要数据。

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