Department of Psychiatry and Behavioral Sciences, Boston Children's Hospital, Boston, Massachusetts, USA.
Pediatric Transplant Center, Boston Children's Hospital, Boston, Massachusetts, USA.
Pediatr Transplant. 2024 Sep;28(6):e14841. doi: 10.1111/petr.14841.
Solid organ transplant recipients experience a period of unique vulnerability during adolescence, when normative developmental changes intersect with health-related variables to influence psychological health.
This article builds on previous reviews of psychological health in solid organ transplant recipients and proposes opportunities for clinical intervention during adolescence.
Transplant recipients often experience neurocognitive changes, particularly with respect to executive functions, that impact health management tasks and autonomous care. Recipients should be monitored for the development of anxiety, depression, and posttraumatic stress symptoms during adolescence, which in turn can negatively impact adherence to immunosuppression. Recent research in posttraumatic growth and resiliency factors may represent a promising avenue of intervention, leveraging normative developmental processes during this time period.
As pediatric transplant providers, adolescence represents a developmental period for targeted interventions to foster adjustment and adherence and promote a successful transition to adult care.
实体器官移植受者在青春期经历一段独特的脆弱期,此时正常的发育变化与健康相关变量相交,影响心理健康。
本文在前瞻性研究综述的基础上,探讨了实体器官移植受者青春期心理健康的相关问题,并提出了临床干预的机会。
移植受者经常经历神经认知变化,特别是执行功能方面的变化,这会影响健康管理任务和自主护理。受者在青春期应监测焦虑、抑郁和创伤后应激症状的发展,这反过来又会影响免疫抑制的依从性。创伤后成长和适应力因素的最新研究可能代表了一种有前途的干预途径,利用这一时期的正常发育过程。
作为儿科移植提供者,青春期是一个有针对性的干预时期,以促进适应和依从性,并促进成功过渡到成人护理。