El-Dalati Sami, Alnabelsi Talal, Gurley John, Cremeans Kelli, Reda Hassan, London-Bounds Tessa, Ogburn Erinn, Sekela Michael
Division of Infectious Diseases, Department of Internal Medicine, University of Kentucky Medical Center, 3101 Beaumont Centre Circle, Lexington, KY 40513, USA.
Gill Heart and Vascular Institute, University of Kentucky Medical Center, Lexington, KY, USA.
Ther Adv Infect Dis. 2024 Aug 7;11:20499361241267124. doi: 10.1177/20499361241267124. eCollection 2024 Jan-Dec.
As a result of the ongoing opioid epidemic, physicians have encountered increasing rates of drug-use-related native tricuspid valve infective endocarditis (DU-TVIE), a complex multi-faceted disease that is best managed by interdisciplinary teams. Despite the large number of patients with DU-TVIE, there is little data to support the optimal treatment strategy with respect to medical and surgical therapy. The recent introduction of percutaneous mechanical aspiration of tricuspid valve vegetations has added another treatment modality that is also of uncertain benefit. Here we review the literature on the management of DU-TVIE and highlight the multi-step treatment approach developed by the multidisciplinary endocarditis team at the University of Kentucky.
由于持续的阿片类药物流行，医生们遇到与药物使用相关的原发性三尖瓣感染性心内膜炎（DU-TVIE）的发病率不断上升，这是一种复杂的多方面疾病，最好由跨学科团队进行管理。尽管有大量DU-TVIE患者，但关于药物和手术治疗的最佳治疗策略的数据却很少。最近引入的经皮三尖瓣赘生物机械抽吸术增加了另一种治疗方式，其益处也不确定。在此，我们回顾了关于DU-TVIE管理的文献，并强调了肯塔基大学多学科心内膜炎团队制定的多步骤治疗方法。
