Mabrouk Moustafa, Atta Islam, Fouda Ahmed, Ismail Khalid, Ismail Taha, Gawish Rasha, Elkassaby Mohammed
Department of Vascular and Endovascular Surgery, Faculty of Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt.
Department of General Surgery, Faculty of Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt.
Vascular. 2025 Aug;33(4):902-909. doi: 10.1177/17085381241273255. Epub 2024 Aug 13.
IntroductionChronic kidney disease (CKD) affects 13% of the global population and requires renal replacement therapy due to ESRD. Hemodialysis (HD) is the most common dialysis modality for ESRD patients, but establishing vascular access is challenging due to high morbidity and mortality rates. Arteriovenous fistulas (AVFs) are the gold standard for vascular access, but many fail due to anastomotic hemodynamics, vein diameter, and anastomatic suture technique. A prospective study was conducted to evaluate the impact of two continuous suturing techniques, the anchor technique and the parachute technique, on AVFs' initial outcomes.MethodsThis randomized, controlled study involved adult patients who presented for AVF creation at our center. We divided the patients into two groups: anchors and parachutes. Four skilled vascular access surgeons performed the procedures. The primary goal was functional maturation of the AVF, defined as an AVF fistula ready to be cannulated with a cannulating vein length of at least 10 cm, a diameter of more than 6 mm, a depth of less than 6 mm, and a flow rate of 600 mL/min. Secondary goals included patency and complications such as bleeding, infection, steal syndrome, and aneurysmal dilatation at the anastomosis site. AVFs were evaluated immediately after surgery and during follow-up visits at the outpatient clinic. A duplex scan was performed to measure flow at various intervals. All patients provided appropriate written consent.ResultThe study involved 186 patients, with 86 excluded. 100 were randomized, with 5 cases losing follow-up and 3 deaths within 12 months. The follow-up continued until January 2024, with a mean of 8.6 months. The Parachute technique shows higher technical success ( value = 0.046) and primary patency at 30 days ( value = 0.014) compared to Anchor, but there is no statistical significance between both groups regarding functional maturation at 6 weeks ( value = 0.352). The parachute technique has a higher hematoma rate than the anchor technique ( value = 0.025), while other complications like intra-operative bleeding, postoperative bleeding, pseudoaneurysm formation, thrombosis, steal syndrome, and seroma formation show no significant differences. Nine patients, five of whom were diabetic and underwent conservative management, exhibited mild to moderate steal syndrome. This suggests an increased risk of steal syndrome among diabetic patients.ConclusionThe parachute technique for AVF creation offers better technical success and short-term primary patency outcomes, while both parachute and anchor techniques are equally effective for long-term functional maturation and overall complication rates.
引言
慢性肾脏病(CKD)影响着全球13%的人口,因终末期肾病(ESRD)需要进行肾脏替代治疗。血液透析(HD)是ESRD患者最常见的透析方式,但由于高发病率和死亡率,建立血管通路具有挑战性。动静脉内瘘(AVF)是血管通路的金标准,但许多内瘘因吻合口血流动力学、静脉直径和吻合缝合技术而失败。本前瞻性研究旨在评估两种连续缝合技术,即锚定技术和降落伞技术,对AVF初始结局的影响。
方法
这项随机对照研究纳入了在我们中心进行AVF创建的成年患者。我们将患者分为两组:锚定组和降落伞组。由四位技术熟练的血管通路外科医生进行手术。主要目标是AVF功能成熟,定义为AVF内瘘准备好进行穿刺,穿刺静脉长度至少为10厘米,直径大于6毫米,深度小于6毫米,血流量为600毫升/分钟。次要目标包括通畅率以及诸如出血、感染、窃血综合征和吻合口处动脉瘤样扩张等并发症。术后立即以及在门诊随访期间对AVF进行评估。在不同时间间隔进行双功超声扫描以测量血流量。所有患者均提供了适当的书面同意书。
结果
该研究纳入186例患者,排除86例。100例患者被随机分组,5例失访,12个月内有3例死亡。随访持续至2024年1月,平均随访8.6个月。与锚定技术相比,降落伞技术显示出更高的技术成功率(P值 = 0.046)和30天时的初始通畅率(P值 = 0.014),但两组在6周时的功能成熟度方面无统计学差异(P值 = 0.352)。降落伞技术的血肿发生率高于锚定技术(P值 = 0.025),而术中出血、术后出血、假性动脉瘤形成、血栓形成、窃血综合征和血清肿形成等其他并发症无显著差异。9例患者出现轻度至中度窃血综合征,其中5例为糖尿病患者并接受了保守治疗。这表明糖尿病患者发生窃血综合征的风险增加。
结论
用于创建AVF的降落伞技术提供了更好的技术成功率和短期初始通畅结局,而降落伞技术和锚定技术在长期功能成熟度和总体并发症发生率方面同样有效。