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肺动脉环扎术对先天性心脏病合并肺动脉高压患者的影响。

Impact of Pulmonary Artery Banding in Patients with Congenital Heart Disease and Pulmonary Hypertension.

作者信息

Zhang Han, Li Gang, Li Qiangqiang, Zuo Yansong, Wang Qiang

机构信息

Pediatric Heart Center, Beijing Anzhen Hospital, Capital Medical University, 100029 Beijing, China.

出版信息

Rev Cardiovasc Med. 2024 Jul 8;25(7):253. doi: 10.31083/j.rcm2507253. eCollection 2024 Jul.

DOI:10.31083/j.rcm2507253
PMID:39139432
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11317308/
Abstract

BACKGROUND

To evaluate the effectiveness of the surgical approach in patients with congenital heart disease and pulmonary hypertension (PH).

METHODS

This was a retrospective clinical review of patients with congenital heart disease and PH who underwent pulmonary artery banding (PAB) at our institution between January 2013 and January 2023.

RESULTS

We identified 219 patients (53.4% males) with a median age of 7 (4.0-15.0) months and a median weight of 6.8 (5.2-9.0) kg at the time of PAB. The median hospital stay was 7.0 (5.0-10.0) days. The in-hospital mortality rate was 4.6%. The median follow-up was 33.0 (17.0-61.0) months. Survival rates were 96.9 2.5% at 60 months and 92.1 6.9% at 120 months post-PAB. 43.8% of patients had a de-banding procedure, and 147 (79.0%) patients received a second-stage procedure (34.7% univentricular, 65.3% biventricular). The mortality rate between stages was 4.3%. 21 (9.6%) patients reached a third-stage procedure. The overall mortality rate was 9.1%.

CONCLUSIONS

PAB is an acceptable strategy for patients with congenital heart disease complicated with PH. The results and outcomes of subsequent univentricular or biventricular procedures are generally good.

摘要

背景

评估手术方法对先天性心脏病合并肺动脉高压(PH)患者的有效性。

方法

这是一项对2013年1月至2023年1月在我院接受肺动脉环缩术(PAB)的先天性心脏病合并PH患者的回顾性临床研究。

结果

我们确定了219例患者(男性占53.4%),PAB时的中位年龄为7(4.0 - 15.0)个月,中位体重为6.8(5.2 - 9.0)kg。中位住院时间为7.0(5.0 - 10.0)天。住院死亡率为4.6%。中位随访时间为33.0(17.0 - 61.0)个月。PAB后60个月的生存率为96.9±2.5%,120个月时为92.1±6.9%。43.8%的患者进行了解环手术,147例(79.0%)患者接受了二期手术(单心室占34.7%,双心室占65.3%)。各阶段之间的死亡率为4.3%。21例(9.6%)患者进行了三期手术。总死亡率为9.1%。

结论

PAB是先天性心脏病合并PH患者可接受的治疗策略。后续单心室或双心室手术的结果和预后总体良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f901/11317308/69eba51105f5/2153-8174-25-7-253-g7.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f901/11317308/ed7d6ca7dc8c/2153-8174-25-7-253-g1.jpg
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本文引用的文献

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Cardiol Young. 2023 Sep;33(9):1627-1633. doi: 10.1017/S1047951122002918. Epub 2022 Sep 14.
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Utility of late pulmonary artery banding in single-ventricle physiology: A mid-term follow-up.晚期肺动脉环扎术在单心室生理中的应用:中期随访
Ann Pediatr Cardiol. 2021 Jan-Mar;14(1):26-34. doi: 10.4103/apc.APC_128_20. Epub 2020 Sep 17.
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Pulmonary artery banding in patients with functional single ventricle associated with pulmonary hypertension.
肺动脉环缩术治疗伴有肺动脉高压的功能性单心室患者。
Clin Exp Hypertens. 2021 May 19;43(4):328-333. doi: 10.1080/10641963.2021.1883048. Epub 2021 Feb 5.
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The effect of body weight in infants undergoing ventricular septal defect closure: A report from the Nationwide Japanese Congenital Surgical Database.体重对室间隔缺损修补术患儿的影响:来自日本全国先天性外科数据库的报告
J Thorac Cardiovasc Surg. 2019 Mar;157(3):1132-1141.e7. doi: 10.1016/j.jtcvs.2018.11.111. Epub 2018 Dec 12.
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Early repair of complete atrioventricular septal defect has better survival than staged repair after pulmonary artery banding: A propensity score-matched study.早期修复完全性房室间隔缺损比肺动脉带环后分期修复的生存率更高:一项倾向评分匹配研究。
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