Pharmacy Department Jasikan District Hospital Ghana Health Service, Jasikan, Ghana.
Department of Pharmacy Practice School of Pharmacy University of Health and Allied Sciences, Ho, Ghana.
Biomed Res Int. 2024 Aug 6;2024:6692421. doi: 10.1155/2024/6692421. eCollection 2024.
Snakebite is a global environmental and occupational hazard and a significant public health threat. In rural areas, snakebite cases often go unreported and undocumented due to the lack of access to well-structured healthcare facilities/infrastructure. In some cases, the need for antisnake venom (ASV) far outstrips supply, negatively affecting treatment outcomes. This study, therefore, assessed the epidemiological characteristics of snakebite cases, their management, and how antivenoms are utilised at the selected hospital in the Jasikan District Hospital. A 6-year retrospective study using secondary data from antivenom return forms (pharmacy records), clinical records (patient folders), the District Health Information Management System-2 (DHIMS-2) database, and consulting room registers was carried out in selected hospitals in the Jasikan District, Oti, Ghana. The predominant symptom of snakebite was localised pain (71.4%). The snakebite commonly occurred at home (19%) and on farms (18%). Of the 98 snakebite cases, ASV was administered to 73 (74.5%) cases. Supportive treatment applied included prophylactic antitetanus immunoglobulin (ATS) (80.6%), prophylactic antibiotics (63%), corticosteroids (80.6%), and analgesics (63%). 95% ( = 94) of complete recoveries were recorded; three were discharged against medical advice, and one was mortality. The supply and use of antivenom were erratic throughout the months of high incidence, partly due to inconsistent availability at the Regional Medical Stores. The average ASV vials and hospital stay duration were 1.23 ± 0.86 vials and 2.67 ± 1.97 days, respectively. Although the peak of snakebites occurs in April, May, and June, the demand for antivenom in April and May exceeded supply. The outcome of most snakebite case management was appropriate, irrespective of inadequate ASV supply in certain months. The erratic antivenom supply should be aligned with seasonal and facility-use patterns to enhance regional snakebite management.
蛇伤是一种全球性的环境和职业危害,也是严重的公共卫生威胁。在农村地区,由于缺乏完善的医疗设施/基础设施,蛇伤病例往往未得到报告和记录。在某些情况下,抗蛇毒血清 (ASV) 的需求远远超过供应,这对治疗结果产生了负面影响。因此,本研究评估了在贾西坎地区医院选定医院的蛇伤病例的流行病学特征、管理情况以及抗蛇毒血清的使用情况。
本研究采用回顾性研究设计,使用从抗蛇毒血清返还表(药房记录)、临床记录(患者文件夹)、地区卫生信息管理系统-2(DHIMS-2)数据库和诊室登记册中获取的二级数据,对加纳奥蒂贾西坎地区选定医院的蛇伤病例进行了 6 年的回顾性研究。
蛇伤的主要症状是局部疼痛(71.4%)。蛇伤常见于家庭(19%)和农场(18%)。在 98 例蛇伤病例中,有 73 例(74.5%)给予了抗蛇毒血清。应用的支持性治疗包括预防破伤风免疫球蛋白(ATS)(80.6%)、预防用抗生素(63%)、皮质类固醇(80.6%)和镇痛药(63%)。记录了 95%(=94)的完全康复;3 例患者出院时医生建议转院,1 例患者死亡。抗蛇毒血清的供应和使用在高发月份不稳定,部分原因是区域医疗用品库的供应不一致。抗蛇毒血清平均使用瓶数和住院时间分别为 1.23±0.86 瓶和 2.67±1.97 天。尽管蛇伤的高峰期在 4 月、5 月和 6 月,但 4 月和 5 月对抗蛇毒血清的需求超过了供应。
尽管某些月份抗蛇毒血清供应不足,但大多数蛇伤病例管理的结果是适当的。抗蛇毒血清的供应应与季节性和设施使用模式保持一致,以加强区域蛇伤管理。