Wu Bing, Sun Xiaoyu, Shao Zeman, Liu Sen, Yang Zhongmei, Zhang Qiuyang, Wei Yanchun
Provincial Engineering Research Center for Biomedical Materials and Advanced Medical Devices, Huaiyin Institute of Technology, Huai'an, Jiangsu, China.
Anal Methods. 2024 Aug 29;16(34):5872-5882. doi: 10.1039/d4ay00811a.
Mercury ions (Hg) are highly toxic heavy metal ions that pose serious health risks to humans when present at concentrations above the safety threshold. Therefore, the development of a rapid and effective Hg detection method is of significant importance. In this study, based on surface plasmon resonance (SPR) technology integrated with COMSOL simulation analysis, a highly sensitive and selective Hg sensing system is constructed. Initially, gold nanoparticles and the surface of a fiber-optic gold film are modified by sodium sulfide (NaS). In the presence of Hg, the sulfur ions on the modified gold film and gold nanoparticles specifically bind to Hg, forming the composite structure Au/S-Hg-S/AuNPS. Due to the strong electromagnetic coupling between the gold nanoparticles and the gold film, a significant SPR wavelength shift occurs. These results show that the Hg sensor has high sensitivity and enhanced selectivity. The detection limit for mercury ions was 8.15 nM, and the recovery rate in real environmental samples was up to 90.1-97.3%. This sensing system provides an alternative method for rapid and accurate determination of mercury content.
汞离子（Hg）是剧毒重金属离子，当浓度高于安全阈值时会对人类健康构成严重风险。因此，开发一种快速有效的汞检测方法具有重要意义。在本研究中，基于表面等离子体共振（SPR）技术并结合COMSOL模拟分析，构建了一种高灵敏度和选择性的汞传感系统。首先，用硫化钠（NaS）对金纳米颗粒和光纤金膜表面进行修饰。在汞存在的情况下，修饰后的金膜和金纳米颗粒上的硫离子与汞特异性结合，形成复合结构Au/S-Hg-S/AuNPS。由于金纳米颗粒与金膜之间存在强电磁耦合，会发生明显的表面等离子体共振（SPR）波长偏移。这些结果表明，该汞传感器具有高灵敏度和增强的选择性。汞离子的检测限为8.15 nM，实际环境样品中的回收率高达90.1-97.3%。该传感系统为快速准确测定汞含量提供了一种替代方法。
