Takeuchi Hajime, Yagi Koki, Tokunaga Naho, Abe Naoki, Matsuno Mariko, Kira Sachino, Hayashi Sotaro, Lee Lifa, To Yoko, Nishiyama Satoshi, Goto Maki, Tsujioka Hiroshi
Department of Obstetrics and Gynecology, Aso Iizuka Hospital, 3-83 Yoshio-machi, Iizuka 820-8505, Japan.
Case Rep Womens Health. 2024 Jul 18;43:e00637. doi: 10.1016/j.crwh.2024.e00637. eCollection 2024 Oct.
The case report describes the management of endometriotic cysts in a woman taking adjuvant tamoxifen. A diagnosis of endometriosis was made at the age of 38, and the condition was initially managed with a low-dose estrogen-progestogen combination; the patient then switched to dienogest at the age of 45. Following a diagnosis of breast cancer at the age of 46, dienogest was stopped and adjuvant tamoxifen treatment started. After 4 months the patient was diagnosed with bilateral ovarian cysts and underwent laparoscopic bilateral salpingo-oophorectomy. Endometriosis was diagnosed in both ovaries on histopathological examination. This case report describes progression of endometriosis in a tamoxifen user.
该病例报告描述了一名服用辅助性他莫昔芬的女性子宫内膜异位囊肿的治疗情况。该女性38岁时被诊断为子宫内膜异位症,最初采用低剂量雌激素 - 孕激素联合治疗;45岁时改用地诺孕素。46岁被诊断为乳腺癌后,停用了地诺孕素并开始辅助性他莫昔芬治疗。4个月后,患者被诊断为双侧卵巢囊肿,并接受了腹腔镜双侧输卵管卵巢切除术。组织病理学检查在双侧卵巢均诊断出子宫内膜异位症。本病例报告描述了一名他莫昔芬使用者子宫内膜异位症的进展情况。