Shimada Yohei, Ochiai Nobuyasu, Hashimoto Eiko, Kajiwara Daisuke, Hiraoka Yu, Inagaki Kenta, Ohtori Seiji, Niki Hisateru
Department of Orthopedic Surgery, St. Marianna University School of Medicine, Kanagawa, Japan.
Department of Orthopedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
JSES Rev Rep Tech. 2024 May 10;4(3):419-423. doi: 10.1016/j.xrrt.2024.04.013. eCollection 2024 Aug.
Continuous local antibiotic perfusion (CLAP) is a method for preserving tissue and function against surgical site infections (SSIs) after shoulder surgery.
To describe the application of the novel CLAP technique to 10 patients with SSIs after shoulder surgery that were not controlled with repeated surgical débridement or elderly patients who are insufficient physical resilience for further surgeries.
CLAP, consisting of gentamicin, was performed for 2 weeks, after which the infection was well-controlled. The white blood cell count and C-reactive protein level improved rapidly within 1 week of initiating CLAP, after which the patients were switched to oral antibiotics for 3 months. None of the patients experienced any adverse events.
CLAP for SSIs after shoulder surgery was successful in preserving implants and grafts. The SSIs were controlled with no adverse events. CLAP may be an important treatment option for SSIs after shoulder surgery.
持续局部抗生素灌注（CLAP）是一种在肩部手术后预防手术部位感染（SSIs）并保留组织和功能的方法。
描述新型CLAP技术在10例肩部手术后发生手术部位感染且经反复手术清创仍无法控制感染的患者，或因身体恢复能力不足而无法进行进一步手术的老年患者中的应用。
使用庆大霉素进行CLAP治疗2周后，感染得到良好控制。开始CLAP治疗后1周内白细胞计数和C反应蛋白水平迅速改善，之后患者改用口服抗生素治疗3个月。所有患者均未出现任何不良事件。
肩部手术后手术部位感染采用CLAP治疗成功保留了植入物和移植物。手术部位感染得到控制且无不良事件发生。CLAP可能是肩部手术后手术部位感染的重要治疗选择。
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