Melaku Berhanu, Gebremichael Berhe, Negash Belay, Kitessa Monas, Kassa Obsan, Dereje Jerman, Kefelegn Reta, Firdisa Dawit
School of Public Health, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.
School of pharmacy, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.
Front Nutr. 2024 Aug 7;11:1369419. doi: 10.3389/fnut.2024.1369419. eCollection 2024.
Acute malnutrition is a major global public health problem, particularly in low-and middle-income countries. A targeted supplementary feeding program is an approach recommended to address moderate acute malnutrition in food-insecure settings. Preventing and treating moderate acute malnutrition requires identifying factors shown to affect the treatment outcome and duration of stay on treatment. This study aimed to determine the time to recovery from moderate acute malnutrition and its predictors among children aged 6-59 months in Fedis Woreda East Hararghe Zone, Eastern Ethiopia, from January 1 to December 31, 2022.
A facility-based retrospective cohort study was conducted on 567 children with moderate acute malnutrition in Fedis Woreda, East Hararghe Zone, eastern Ethiopia. A multi-stage sampling technique was employed, and data was collected using a structured checklist. Data were extracted from randomly selected records after obtaining ethical clearance. Data were cleaned, coded, entered into EpiData 4.6, and analyzed using STATA/SE version 14. Descriptive statistics and analytic analysis schemes, including bivariable and multivariable Cox proportional hazards models, were conducted, and finally, statistical significance was considered at < 0.05.
The overall median time to recovery was 16 weeks. The major predicting factors for time to recovery among children aged 6-59 months were admission with a mid-upper arm circumference of 12.1-12.4 centimeters (AHR = 1.02, 95% CI: 1.01-1.19), access to transportation to facilities (AHR = 0.62, 95% CI: 0.36-0.81), children using specialized nutritious foods (RUSF; AHR = 1.96, 95% CI: 1.36-3.11), and children who had diarrhea (AHR = 0.4, 95% CI: 0.31-0.71).
The study found a median recovery time of 16 weeks for children with targeted supplementary feeding. Significant predictors included admission with a MUAC of 12.1-12.4 centimeters, transportation access, RUSF use, and the presence of diarrhea. These findings highlighted the importance of these factors in determining and improving recovery from moderate-acute malnutrition.
急性营养不良是一个重大的全球公共卫生问题，在低收入和中等收入国家尤为突出。有针对性的补充喂养计划是一种在粮食不安全环境中应对中度急性营养不良的推荐方法。预防和治疗中度急性营养不良需要确定那些已被证明会影响治疗结果和治疗持续时间的因素。本研究旨在确定2022年1月1日至12月31日期间，埃塞俄比亚东部哈拉尔格东部地区费迪斯县6至59个月大儿童从中度急性营养不良中恢复的时间及其预测因素。
在埃塞俄比亚东部哈拉尔格东部地区费迪斯县对567名中度急性营养不良儿童进行了一项基于机构的回顾性队列研究。采用多阶段抽样技术，使用结构化清单收集数据。在获得伦理批准后，从随机选择的记录中提取数据。对数据进行清理、编码，录入EpiData 4.6，并使用STATA/SE 14版本进行分析。进行了描述性统计和分析分析方案，包括双变量和多变量Cox比例风险模型，最后，以<0.05为统计学显著性水平。
总体恢复的中位时间为16周。6至59个月大儿童恢复时间的主要预测因素是入院时上臂中部周长为12.1 - 12.4厘米（风险比=1.02，95%置信区间：1.01 - 1.19）、有前往医疗机构的交通条件（风险比=0.62，95%置信区间：0.36 - 0.81）、儿童使用特殊营养食品（即即食治疗性食品；风险比=1.96，95%置信区间：1.36 - 3.11）以及患有腹泻的儿童（风险比=0.4，95%置信区间：0.31 - 0.71）。
该研究发现接受有针对性补充喂养的儿童中位恢复时间为16周。重要的预测因素包括入院时上臂中部周长为12.1 - 12.4厘米、交通条件、使用即食治疗性食品以及腹泻情况。这些发现突出了这些因素在确定和改善中度急性营养不良恢复情况方面的重要性。
