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带状疱疹感染后牙槽骨坏死和牙齿脱落:一例报告并文献复习

Alveolar osteonecrosis and tooth exfoliation following herpes zoster infection: A case report and review of the literature.

作者信息

Sun Z, Chen E, Yi D, Xiao S

机构信息

State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Department of Periodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.

出版信息

Aust Dent J. 2025 Mar;70(1):78-87. doi: 10.1111/adj.13031. Epub 2024 Aug 22.

Abstract

Tooth loss and osteonecrosis of the jaw are a serious and rare oral complications of herpes zoster infection, particularly in immunocompetent individuals. An immunocompetent 58-year-old male patient presented with a sudden exfoliation of almost all the teeth in his right mandible 2 days prior. Three weeks before this event, he had been diagnosed with herpes zoster infection, which led to irreversible necrosis on the right side of his mandible over 3 months. He was subsequently diagnosed with the osteonecrosis of the right mandible following herpes zoster infection and received aggressive treatment including medication, laser therapy and surgery. We present here our insights into the risk factors, differential diagnosis, pathogenesis and treatment options for this rare complication based on our case and latest literature review.

摘要

牙齿脱落和颌骨骨坏死是带状疱疹感染严重且罕见的口腔并发症,尤其在免疫功能正常的个体中。一名58岁免疫功能正常的男性患者,在2天前出现右下颌几乎所有牙齿突然脱落。在此事件发生前三周,他被诊断为带状疱疹感染,该感染在3个月内导致其右下颌不可逆坏死。随后他被诊断为带状疱疹感染后右下颌骨坏死,并接受了包括药物治疗、激光治疗和手术在内的积极治疗。基于我们的病例和最新文献综述,我们在此阐述对这种罕见并发症的危险因素、鉴别诊断、发病机制和治疗选择的见解。

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