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爱尔兰初产妇产后出血(PPH)的趋势、原因及相关因素:对 100 万例医院分娩的回顾。

Trends, causes and factors associated with primary Postpartum Haemorrhage (PPH) in Ireland: A review of one million hospital childbirths.

机构信息

University College Cork, School of Nursing and Midwifery, Cork, Ireland.

National Perinatal Epidemiology Centre (NPEC), University College Cork (UCC) , Ireland.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2024 Oct;301:258-263. doi: 10.1016/j.ejogrb.2024.08.011. Epub 2024 Aug 22.

Abstract

OBJECTIVE

To analyse temporal trends for primary Postpartum Haemorrhage (PPH), Major Obstetric Haemorrhage (MOH) between 2005 and 2021 and to examine the causes and factors contributing to the risk of PPH during 2017-2021.

METHODS

International ICD-10-AM diagnostic codes from hospital discharge records were used to identify cases of PPH. Temporal trends in PPH and MOH incidence were illustrated graphically. Poisson regression was used to assess the time trends and to examine factors associated with the risk of PPH during 2017-2021.

RESULTS

A total of 1,003,799 childbirth hospitalisations were recorded; 5.6% included a diagnosis of primary PPH. Risk increased almost fourfold from 2.5% in 2005 to 9.6% in 2021. The ICD-10 AM code for other immediate primary PPH was recorded for 85% of PPH cases in 2017-2021 whereas a diagnosis of uterine inertia/atony was associated with just 3.6% of the cases. Respectively, trauma-related, tissue-related and thrombin-related causes were associated with one third, 4.2% and 0.5% of cases. A wide range of factors relating to the woman including comorbidities, mode of delivery, labour-related interventions and associated traumas increased risk of PPH but placental complications, especially morbidly adherent placenta, were strong risk factors.

CONCLUSIONS

Improvement in detection and anticipation of placental complications may be effective in addressing the increasing trend of PPH, however, the trends of increasing C-sections and other interventions may also need to be addressed while staff education and quality improvement projects will have a role to play.

摘要

目的

分析 2005 年至 2021 年期间原发性产后出血(PPH)和主要产科出血(MOH)的时间趋势,并研究 2017-2021 年期间导致 PPH 风险的原因和因素。

方法

使用医院出院记录中的国际疾病分类第 10 次修订版(ICD-10-AM)诊断代码来识别 PPH 病例。以图形方式说明 PPH 和 MOH 发生率的时间趋势。使用泊松回归评估时间趋势,并研究 2017-2021 年期间与 PPH 风险相关的因素。

结果

共记录了 1003799 例分娩住院病例;其中 5.6%包括原发性 PPH 的诊断。风险从 2005 年的 2.5%增加到 2021 年的 9.6%,几乎增加了四倍。2017-2021 年期间,85%的 PPH 病例记录了 ICD-10 AM 代码其他即刻原发性 PPH,而子宫无力/弛缓的诊断仅与 3.6%的病例相关。分别来说,与创伤相关、组织相关和凝血酶相关的原因与三分之一、4.2%和 0.5%的病例相关。与妇女有关的各种因素,包括合并症、分娩方式、与分娩相关的干预措施和相关创伤,增加了 PPH 的风险,但胎盘并发症,特别是黏附性胎盘,是强烈的风险因素。

结论

提高对胎盘并发症的检测和预测能力可能有助于解决 PPH 增加的趋势,但剖宫产和其他干预措施的趋势也需要解决,同时员工教育和质量改进项目也将发挥作用。

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