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[90岁以上超高龄髋部骨折患者术后1年内的死亡危险因素]

[Risk factors for postoperative mortality within 1 year in more than 90-year-old super advanced age patients with hip fractures].

作者信息

Chai Sha-Sha, Hu Jun-Wei, Han Lei

机构信息

Department of Orthopaedics, Jiangnan Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine, Traditional Chinese Medical Hospital of Xiaoshan, Hangzhou 311201, Zhejiang, China.

Department of Anesthesiology, Jiangnan Hospital Affiliated to Zhejiang University of Traditional Chinese Medicine, Traditional Chinese Medical Hospital of Xiaoshan, Hangzhou 311201, Zhejiang, China.

出版信息

Zhongguo Gu Shang. 2024 Aug 25;37(8):833-37. doi: 10.12200/j.issn.1003-0034.20231225.

Abstract

OBJECTIVE

To investigate the 1 year mortality after hip fractures in super advanced age patients and summarize the death associated risk factors in order to provide basis for targeted intervention countermeasures.

METHODS

The clinical data of 332 super advanced age patients with femoral neck or intertrochanteric fractures treated by hip replacement or intramedullary femoral nail fixation from January 2015 to January 2023 were retrospectively analyzed. There were 128 males and 204 females with the mean age of (92.2±2.5) years ranging from 90 to 103 years old. Among them, 92 cases died within 1 year after surgery. Correlation with the occurrence of death on age, gender, body mass index, fracture type, treatment method, timing of operation, preoperative hemoglobin and serum albumin level, operation time, combined medical diseases, pre-injury mobilityand American Society of Anesthesiology(ASA) classification were analyzed. The risk factors of death within 1 year after operation were screened by univariate analysis. The results were entered into the multivariate Logistic regression analysis, screening the high risk factors for 1 year mortality after hip fractures.

RESULTS

The mortality of super advanced age patients with hip fracture within 1 year after surgery accounted for 27.7%(92/332). Univariate analysis showed high body mass index, long interval from injury to surgery, low preoperative serum albumin levels, inability to walk independently before injury, accompanied by heart failure, pulmonary infection, obstructive pulmonary disease, stroke, and a higher proportion of ASA grades Ⅲ-Ⅳ. Multivariate Logistic regression analysis showed preoperative serum albumin below 30g g·L[=2.973, 95%(2.461, 5.344), =0.039], inability to walk independently before injury [=3.519, 95%(2.224, 5.413), =0.018], heart function grade C-D[=4.213, 95%(2.952, 6.99), =0.021], pulmonary infection[=3.927, 95%(2.187, 7.731), =0.016] and ASA Ⅲ-Ⅳ[=5.124, 95%(3.092, 8.235), =0.032] were the independent risk factors for death within 1 year in super advanced age patients with hip fractures.

CONCLUSION

Preoperative serum albumin below 30g.L-1, poor preinjury activity, heart function grade C-D, pulmonary infection, and ASA grade Ⅲ-Ⅳ are independent risk factors for postoperative mortality in super advanced age patients with hip fractures.

摘要

目的

探讨超高龄患者髋部骨折后1年的死亡率,总结死亡相关危险因素,为针对性干预措施提供依据。

方法

回顾性分析2015年1月至2023年1月采用髋关节置换或股骨近端髓内钉固定治疗的332例超高龄股骨颈或转子间骨折患者的临床资料。其中男性128例,女性204例,平均年龄(92.2±2.5)岁,年龄范围90至103岁。其中92例在术后1年内死亡。分析年龄、性别、体重指数、骨折类型、治疗方法、手术时机、术前血红蛋白和血清白蛋白水平、手术时间、合并内科疾病、伤前活动能力及美国麻醉医师协会(ASA)分级与死亡发生的相关性。通过单因素分析筛选术后1年内死亡的危险因素。将结果纳入多因素Logistic回归分析,筛选髋部骨折后1年死亡率的高危因素。

结果

超高龄髋部骨折患者术后1年内死亡率为27.7%(92/332)。单因素分析显示体重指数高、受伤至手术间隔时间长、术前血清白蛋白水平低、伤前不能独立行走、伴有心力衰竭、肺部感染、阻塞性肺疾病、中风以及ASAⅢ-Ⅳ级比例较高。多因素Logistic回归分析显示术前血清白蛋白低于30g·L[=2.973,95%(2.461,5.344),=0.039]、伤前不能独立行走[=3.519,95%(2.224,5.413),=0.018]、心功能C-D级[=4.213,95%(2.952,6.99),=0.021]、肺部感染[=3.927,95%(2.187,7.731),=0.016]和ASAⅢ-Ⅳ级[=5.124,95%(3.092,8.235),=0.032]是超高龄髋部骨折患者术后1年内死亡的独立危险因素。

结论

术前血清白蛋白低于30g·L-1、伤前活动能力差、心功能C-D级、肺部感染和ASAⅢ-Ⅳ级是超高龄髋部骨折患者术后死亡的独立危险因素。

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