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《他汀不耐受患者诊断与管理策略中国专家共识》解读:助力中国人群血脂管理的指导文件

Interpretation of Chinese Expert Consensus on the Diagnosis and Management Strategy of Patients with Statin Intolerance: A guiding file for helping to lipid management for Chinese population.

作者信息

Li Jian-Jun

机构信息

Cardiometabolic Center, National Center for Cardiovascular Disease, Chinese Academy of Medical Science, Fuwai Hospital, Beijing, China.

出版信息

J Geriatr Cardiol. 2024 Jul 28;21(7):713-715. doi: 10.26599/1671-5411.2024.07.006.

Abstract

It is well-known that elevated low-density lipoprotein cholesterol (LDL-C) is a causal risk factor for atherosclerotic cardiovascular disease (ASCVD), statins are cornerstone drugs for the cause-based treatment of ASCVD, which has created a new era for ASCVD therapy. However, statin intolerance is not clinically uncommon, which there are several issues with confusion and misunderstandings. Hence, a file named Chinese Expert Consensus on the Diagnosis and Management Strategy of Patients With Statin Intolerance, like a navigator, has recently been published written by a team of experts from the Cardiovascular Metabolic Medicine Professional Committee, Expert Committee of the National Center for Cardiovascular Diseases aiming to enhance the standardized clinical application of statins and improve the prevention and clinical outcome. In this article, author briefly summarized the key points of above consensus in order to helping to comprehending the content of the consensus suggestions.

摘要

众所周知,低密度脂蛋白胆固醇(LDL-C)升高是动脉粥样硬化性心血管疾病(ASCVD)的一个因果危险因素,他汀类药物是基于病因治疗ASCVD的基石药物,这开创了ASCVD治疗的新时代。然而,他汀不耐受在临床上并不少见,存在一些混淆和误解的问题。因此,心血管代谢医学专业委员会、国家心血管病中心专家委员会的一组专家最近发表了一份名为《他汀不耐受患者诊断和管理策略中国专家共识》的文件,旨在加强他汀类药物的标准化临床应用,改善预防和临床结局。在本文中,作者简要总结了上述共识的要点,以帮助理解共识建议的内容。

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2023 Chinese guideline for lipid management.《2023年中国血脂管理指南》
Front Pharmacol. 2023 Aug 29;14:1190934. doi: 10.3389/fphar.2023.1190934. eCollection 2023.

本文引用的文献

2
2023 Chinese guideline for lipid management.《2023年中国血脂管理指南》
Front Pharmacol. 2023 Aug 29;14:1190934. doi: 10.3389/fphar.2023.1190934. eCollection 2023.
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Statin Intolerance Clinical Guide 2018.《2018年他汀类药物不耐受临床指南》
J Atheroscler Thromb. 2020 Apr 1;27(4):375-396. doi: 10.5551/jat.50948. Epub 2019 Oct 4.

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