Dwivedi Medha, Pawar Aiswarya, Kori Mahima, Yadav Hitendra, Dwivedi Manish
Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow Campus, Gomtinagar Extension, Lucknow, 226028, India.
Prescience Insilico Private Limited, Bangalore, India.
Infect Disord Drug Targets. 2025;25(2):e18715265305007. doi: 10.2174/0118715265305007240718081727.
Infectious disorders known as Neglected Tropical Diseases (NTDs) initially affect the world's underprivileged citizens. They have been disregarded for many years, first as a result of a general indifference to such a developing world and, more recently, as an outcome of the intense attention on AIDS, TB, and malaria. Tropical diseases mostly affect the region where health and hygiene are sacrificed, and most of the population lacks access to sufficient food and living resources. WHO has drafted and released the directions for regulation, prevention, and successful eradication of NTDs as per the revised roadmap of 2021-2030. This shifts from vertical disease programs to integrated cross-cutting methods. In the current work, we have provided comprehensive information on various aspects of neglected tropical diseases, including the clinical management of NTDs. This encompasses the causative agent of the diseases, their symptoms, pathogenesis, diagnosis, treatment, prognosis, and epidemiological perspective of major NTDs. This review will shed light on several perspectives of NTDs having influential roles in proposing strategies to control and treat them around the world.
被称为“被忽视的热带病”（NTDs）的传染性疾病最初影响着世界上的贫困公民。多年来，它们一直被忽视，起初是由于对发展中世界普遍漠不关心，最近则是由于对艾滋病、结核病和疟疾的高度关注。热带病主要影响那些牺牲健康和卫生的地区，而且大多数人口无法获得足够的食物和生活资源。世界卫生组织已根据2021 - 2030年修订路线图起草并发布了关于被忽视热带病的监管、预防和成功根除的指导方针。这从垂直的疾病项目转向了综合的跨领域方法。在当前的工作中，我们提供了关于被忽视热带病各方面的全面信息，包括这些疾病的临床管理。这涵盖了疾病的病原体、症状、发病机制、诊断、治疗、预后以及主要被忽视热带病的流行病学情况。这篇综述将阐明被忽视热带病在提出全球控制和治疗策略方面具有重要影响的几个观点。
