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漂亮的纳米花作为用于生物医学和生物分析应用中传感的新型通用分析工具的作用。

Role of pretty nanoflowers as novel versatile analytical tools for sensing in biomedical and bioanalytical applications.

作者信息

Dadi Seyma, Ocsoy Ismail

机构信息

Department of Nanotechnology Engineering Abdullah Gül University Kayseri Turkey.

Department of Analytical Chemistry Faculty of Pharmacy Erciyes University Kayseri Turkey.

出版信息

Smart Med. 2024 Feb 26;3(1):e20230040. doi: 10.1002/SMMD.20230040. eCollection 2024 Feb.

DOI:10.1002/SMMD.20230040
PMID:39188519
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11236047/
Abstract

In recent years, an encouraging breakthrough in the synthesis of immobilized enzymes in flower-shaped called "organic-inorganic hybrid nanoflowers (hNFs)" with greatly enhanced catalytic activity and stability were reported. Although, these hNFs were discovered by accident, the enzymes exhibited highly enhanced catalytic activities and stabilities in the hNFs compared with the free and conventionally immobilized enzymes. Herein, we rationally utilized the catalytic activity of the hNFs for analytical applications. In this comprehensive review, we covered the design and use of the hNFs as novel versatile sensors for electrochemical, colorimetric/optical and immunosensors-based detection strategies in analytical perspective.

摘要

近年来，有报道称在合成称为“有机-无机杂化纳米花（hNFs）”的花状固定化酶方面取得了令人鼓舞的突破，其催化活性和稳定性大大增强。尽管这些hNFs是偶然发现的，但与游离酶和传统固定化酶相比，酶在hNFs中表现出高度增强的催化活性和稳定性。在此，我们合理利用hNFs的催化活性用于分析应用。在这篇全面的综述中，我们从分析角度涵盖了hNFs作为新型多功能传感器在电化学、比色/光学和基于免疫传感器的检测策略中的设计和应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/484d/11236047/31bcc3569bb3/SMMD-3-e20230040-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/484d/11236047/2fbfbfde0253/SMMD-3-e20230040-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/484d/11236047/3c363d87c7ad/SMMD-3-e20230040-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/484d/11236047/ddfbb523cc91/SMMD-3-e20230040-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/484d/11236047/dd787ae869dc/SMMD-3-e20230040-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/484d/11236047/9f7b1bb51d18/SMMD-3-e20230040-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/484d/11236047/6b0597bd52df/SMMD-3-e20230040-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/484d/11236047/31bcc3569bb3/SMMD-3-e20230040-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/484d/11236047/2fbfbfde0253/SMMD-3-e20230040-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/484d/11236047/3c363d87c7ad/SMMD-3-e20230040-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/484d/11236047/ddfbb523cc91/SMMD-3-e20230040-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/484d/11236047/dd787ae869dc/SMMD-3-e20230040-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/484d/11236047/9f7b1bb51d18/SMMD-3-e20230040-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/484d/11236047/6b0597bd52df/SMMD-3-e20230040-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/484d/11236047/31bcc3569bb3/SMMD-3-e20230040-g009.jpg

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