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新冠疫情的遗产:来自阿巴拉契亚学术医疗中心对母婴健康的影响

The Legacy of the COVID-19 Pandemic: Impact on Infant and Maternal and Health from an Appalachian Academic Medical Center.

作者信息

Haarbauer Kelsey, Burke Rebecca, Smith M Cody, Miller Audrey N, Moran Patricia N, Moise Alicia A, Cottrell Lesley, Polak Mark J

机构信息

Department of Pediatrics, West Virginia University School of Medicine, Morgantown, WV 26506, USA.

Division of Neonatology, Department of Pediatrics, Penn State College of Medicine, Penn State Health Children's Hospital, Hershey, PA 17033, USA.

出版信息

Children (Basel). 2024 Jul 30;11(8):924. doi: 10.3390/children11080924.

Abstract

BACKGROUND/OBJECTIVES: The COVID-19 pandemic period from 2020 to 2022 had a significant impact on maternal infant health with mothers impacted more than their infants. We questioned whether there have been any lingering effects from the pandemic.

METHODS

We examined intermediate and long-term pandemic effects on maternal and neonatal outcomes before, during, and after the COVID-19 pandemic period. We reviewed mother-infant pairs from the following three epochs: (1) the pre-COVID-19 period, (2) the COVID-19 pandemic period, and (3) the post-pandemic period. The Case Mix Index (CMI) for the neonates from all three epochs were detailed.

RESULTS

Post-pandemic, we noted a rising trend of LGA infants (10%) and an increase in SGA infants (13%). For women in 2023, we noted an increase in hypertension, preeclampsia, diabetes, and a higher BMI than in the pre-pandemic period. There have also been more congenital anomalies (9%), and neonatal CMI increased in the post-pandemic period.

CONCLUSIONS

Well after the pandemic period, maternal-infant health continues to be affected. For women, the increase in hypertension and diabetes during pregnancy is concerning. For infants, being LGA or SGA may have long-term consequences. The post-pandemic increase in infants with congenital anomalies compared to the pre-pandemic era is an area that needs ongoing review.

摘要

背景/目的:2020年至2022年的新冠疫情期间对母婴健康产生了重大影响,母亲受到的影响比婴儿更大。我们质疑疫情是否产生了任何持续影响。

方法

我们研究了新冠疫情期间及之前和之后疫情对母婴结局的中期和长期影响。我们回顾了来自以下三个时期的母婴对:(1)新冠疫情前时期,(2)新冠疫情时期,以及(3)疫情后时期。详细列出了所有三个时期新生儿的病例组合指数(CMI)。

结果

疫情后,我们注意到大于胎龄儿(LGA)婴儿的比例呈上升趋势(10%),小于胎龄儿(SGA)婴儿有所增加(13%)。对于2023年的女性,我们注意到高血压、先兆子痫、糖尿病有所增加,且体重指数(BMI)高于疫情前时期。先天性异常也有所增加(9%),疫情后时期新生儿CMI升高。

结论

在疫情结束很久之后,母婴健康仍持续受到影响。对于女性而言,孕期高血压和糖尿病的增加令人担忧。对于婴儿来说,成为LGA或SGA可能会有长期后果。与疫情前时代相比,疫情后先天性异常婴儿的增加是一个需要持续审查的领域。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/69c7/11352866/02d72f17ad43/children-11-00924-g001.jpg

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