School of Sport and Health, Shandong Sport University, Jinan 250102, China.
School of Sport and Health Science, Xi'an Physical Education University, Xi'an 710068, China.
Genes (Basel). 2024 Aug 13;15(8):1068. doi: 10.3390/genes15081068.
This investigation aimed to explore the relationship between Chinese elite wrestlers and the polymorphic loci of explosive strength genes, and to further explore the feasibility of its application to athlete selection. The snapshot technique was used to resolve the polymorphic loci of explosive power genes in the wrestler group (59 elite wrestlers) and the control group (180 ordinary college students), and to analyze the genotype frequencies and allele frequencies of each group. A chi-square test was performed on the genotype and allele distribution data of each group to analyze the loci of explosive power genes that were associated with elite wrestlers. The loci that had an association with elite wrestlers were combined with the genotyping data, and the dominance ratios of the genotypes were calculated using the chi-square test to determine the dominant genotypes associated with elite wrestlers. The gene rs2228570 locus exhibited statistically significant differences in genotype and allele distributions between elite wrestlers and the general population ( < 0.01). At the rs2228570 locus of the gene, the difference between the CC genotype and other genotypes was statistically significant ( < 0.05). The rs2228570 locus of the gene was identified as the locus associated with Chinese elite wrestlers. The polymorphism of the gene can be used as a biomarker for Chinese wrestlers, and the CC genotype can be used as a molecular marker for the selection of Chinese elite athletes in this sport. However, expanding the sample size of elite athletes is necessary to further validate the scientific validity and feasibility of these findings.
本研究旨在探讨中国优秀摔跤运动员与爆发力基因多态性位点的关系，进一步探讨其在运动员选材中的应用可行性。采用瞬时采样技术解析摔跤运动员组（59 名优秀摔跤运动员）和对照组（180 名普通大学生）的爆发力基因多态性位点，分析各组的基因型频率和等位基因频率。对各组基因型和等位基因分布数据进行卡方检验，分析与优秀摔跤运动员相关的爆发力基因位点。将与优秀摔跤运动员相关的位点与基因分型数据相结合，采用卡方检验计算基因型的优势比，确定与优秀摔跤运动员相关的优势基因型。基因 rs2228570 位点的基因型和等位基因分布在优秀摔跤运动员和普通人群之间存在统计学差异（<0.01）。在基因 rs2228570 位点，CC 基因型与其他基因型之间的差异具有统计学意义（<0.05）。基因 rs2228570 位点被确定为与中国优秀摔跤运动员相关的位点。基因的多态性可作为中国摔跤运动员的生物标志物，CC 基因型可作为该运动项目中国优秀运动员选拔的分子标记。然而，需要扩大优秀运动员的样本量，以进一步验证这些发现的科学有效性和可行性。
