Rao Chintada Bhaskara, Keahey Pelham, Uribe-Patarroyo Néstor, Bouma Brett E, Villiger Martin
Opt Lett. 2024 Sep 1;49(17):4979-4982. doi: 10.1364/OL.533271.
Speckle degrades the quality of optical coherence tomography (OCT) images and impedes their visual interpretation. Current hardware methods for speckle suppression necessitate difficult hardware modifications. As a result, algorithmic approaches for speckle suppression generally lack validation or training with physically meaningful ground truth. Here, we demonstrate angular compounding through tilting of the sample with a motorized rotation stage. Tomograms acquired at different tilt angles are related to each other through a physics-informed affine map, which can be retrieved directly from the measurement data. Using a mechanical sample tilting stage obviates the need to alter the OCT hardware and enables effective angular compounding with existing OCT instruments.
散斑会降低光学相干断层扫描（OCT）图像的质量，并妨碍其视觉解读。当前用于散斑抑制的硬件方法需要进行复杂的硬件修改。因此，散斑抑制的算法方法通常缺乏基于物理意义明确的真实数据的验证或训练。在此，我们展示了通过使用电动旋转台倾斜样品来进行角度复合。在不同倾斜角度获取的断层图像通过基于物理知识的仿射映射相互关联，该映射可直接从测量数据中获取。使用机械样品倾斜台无需改变OCT硬件，并能与现有的OCT仪器实现有效的角度复合。
