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血胆症作为胆管细胞癌的首发表现。

Haemobilia as a primary presentation of cholangiocarcinoma.

机构信息

The University of Sydney Discipline of Surgery, Sydney, New South Wales, Australia

Urology, Grampians Health, Ballarat, Victoria, Australia.

出版信息

BMJ Case Rep. 2024 Aug 29;17(8):e260524. doi: 10.1136/bcr-2024-260524.

Abstract

We present a case of haemobilia as a primary presentation for underlying cholangiocarcinoma. A man in his 50s initially presented to emergency with Quincke's triad, RUQ pain, jaundice and UGI bleeding. The initial diagnosis of haemobilia was made on endoscopic retrograde cholangiopancreatography (ERCP) on primary presentation, but the presence of blood and the recurrent clot obstruction of the biliary tract made the underlying diagnosis extremely difficult, resulting in the patient having 4 ERCP, 1 spyglass and multiple CTs and magnetic resonance cholangiopancreatography. Eventually, the patient underwent a Whipple's procedure without tissue diagnosis, confirming cholangiocarcinoma on histopathology. This case emphasises the difficulty of diagnosis of underlying malignancy in the setting of haemobilia, the benefit of multidisciplinary meeting discussions to support significant interventions and the need to be cautious and curious when managing atypical presentations.

摘要

我们报告了一例以胆血为主要表现的胆管癌。一名 50 多岁的男性最初因昆克三联征(RUQ 疼痛、黄疸和 UGI 出血)就诊于急诊。最初的诊断为内镜逆行胰胆管造影(ERCP)时的胆血,但是血液的存在和胆道反复出现的血栓阻塞使明确诊断变得极其困难,导致该患者接受了 4 次 ERCP、1 次胆道镜检查和多次 CT 和磁共振胰胆管成像。最终,患者接受了胰十二指肠切除术,但没有进行组织诊断,组织病理学证实为胆管癌。本病例强调了在胆血情况下诊断潜在恶性肿瘤的困难,多学科会议讨论对支持重大干预措施的益处,以及在处理非典型表现时需要谨慎和好奇。

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