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保留生育功能治疗及随访宫颈癌、卵巢癌和交界性卵巢肿瘤患者:来自 ESGO、ESHRE 和 ESGE 的指南。

Fertility-sparing treatment and follow-up in patients with cervical cancer, ovarian cancer, and borderline ovarian tumours: guidelines from ESGO, ESHRE, and ESGE.

机构信息

Department of Gynecological Surgery, Gustave Roussy Cancer Campus, Villejuif, France; Université Paris Saclay, Paris, France.

Department of Women, Children, and Public Health Sciences, Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy.

出版信息

Lancet Oncol. 2024 Nov;25(11):e602-e610. doi: 10.1016/S1470-2045(24)00262-6. Epub 2024 Aug 28.

Abstract

The European Society of Gynaecological Oncology, the European Society of Human Reproduction and Embryology, and the European Society for Gynaecological Endoscopy jointly developed clinically relevant and evidence-based guidelines focusing on key aspects of fertility-sparing strategies and follow-up of patients with cervical cancers, ovarian cancers, and borderline ovarian tumours. The developmental process of these guidelines is based on a systematic literature review and critical appraisal involving an international multidisciplinary development group consisting of 25 experts from relevant disciplines (ie, gynaecological oncology, oncofertility, reproductive surgery, endoscopy, imaging, conservative surgery, medical oncology, and histopathology). Before publication, the guidelines were reviewed by 121 independent international practitioners in cancer care delivery and patient representatives. The guidelines comprehensively cover oncological aspects of fertility-sparing strategies during the initial management, optimisation of fertility results and infertility management, and the patient's desire for future pregnancy and beyond.

摘要

欧洲妇科肿瘤学会、欧洲人类生殖与胚胎学会和欧洲妇科内镜学会联合制定了具有临床相关性和基于证据的指南,重点关注宫颈癌、卵巢癌和交界性卵巢肿瘤患者的保留生育力策略和随访的关键方面。这些指南的制定过程基于系统的文献回顾和批判性评价,涉及一个由 25 名相关学科(即妇科肿瘤学、肿瘤生育力、生殖外科、内镜、影像学、保守性手术、肿瘤内科和组织病理学)专家组成的国际多学科发展小组。在发布之前,这些指南由 121 名从事癌症护理和患者代表的独立国际从业者进行了审查。这些指南全面涵盖了初始管理期间保留生育力策略的肿瘤学方面、优化生育结果和不孕管理,以及患者对未来妊娠的渴望及其后续问题。

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