This study aimed to investigate the influence of the ZnO concentration on the structure of a membrane for effluent filtration, varying this concentration from 0% to 3%. To analyze the results, X-ray diffraction tests, Fourier-transform infrared spectroscopy, apparent porosity, atomic force microscopy, and scanning electron microscopy were used, all of which were employed for the characterization of the produced membranes. The solution simulating the effluent was analyzed before and after the filtration process to assess the filtration results. The conducted tests reported results for filtered solution flow, turbidity, pH, dissolved oxygen, and electrical conductivity. All these results indicated that the membrane with the best performance in terms of cleanliness and the amount of filtered effluent was the one produced with a 13% hybrid polysulfone loaded with 1% ZnO in its structure.