Briciu Violeta, Kalmár Zsuzsa, Ieremia Anca, Lupșe Mihaela, Flonta Mirela, Muntean Monica, Cismaru Cristina, Horvat Melinda, Rădulescu Amanda, Topan Adriana, Jianu Cristian, Ionică Angela Monica
Clinical Hospital of Infectious Diseases of Cluj-Napoca, 400348 Cluj-Napoca, Romania.
Department of Infectious Diseases and Epidemiology, "Iuliu Hațieganu" University of Medicine and Pharmacy, 4000348 Cluj-Napoca, Romania.
Food Waterborne Parasitol. 2024 Aug 3;36:e00240. doi: 10.1016/j.fawpar.2024.e00240. eCollection 2024 Sep.
Humans may become accidental dead-end hosts for a series of zoonotic foodborne parasites, of which , spp., spp., and are of major public health interest, due to their potential pathological implications. The aims of the study were to evaluate the exposure to these pathogens in north-western Romania, and to investigate their potential association to risk factors. From June 2022 to January 2024, 554 patients admitted to a tertiary hospital in north-western Romania were screened for the presence of IgG antibodies against , spp., , and by ELISA, and potential risks were assessed using a questionnaire. Overall, 225 samples (40.6%) were positive for at least one pathogen. The highest seroprevalence for IgG was found for (33.9%), followed by spp. (9.1%), (2.9%) and (1.1%). For , raw meat consumption was associated with positivity. For increased age, rural environment, contact with cats, consumption of unwashed fruits/vegetables and drinking water from unverified sources were significantly associated to seropositivity. The present study provides new insights into the epidemiological status of zoonotic foodborne parasite in Romania, underlining the need to increase awareness on the importance of water, sanitation and food habits in relation with this neglected pathology.
人类可能会成为一系列食源性人畜共患寄生虫的偶然终末宿主，其中，由于其潜在的病理学影响，某些种类的寄生虫对公共卫生具有重大意义。本研究的目的是评估罗马尼亚西北部地区这些病原体的暴露情况，并调查它们与风险因素之间的潜在关联。2022年6月至2024年1月，对罗马尼亚西北部一家三级医院收治的554名患者进行了酶联免疫吸附测定（ELISA），以筛查针对某些寄生虫的IgG抗体，并通过问卷调查评估潜在风险。总体而言，225份样本（40.6%）至少对一种病原体呈阳性。IgG血清阳性率最高的是某种寄生虫（33.9%），其次是某些种类的寄生虫（9.1%）、另一种寄生虫（2.9%）和又一种寄生虫（1.1%）。对于某种寄生虫，食用生肉与阳性结果相关。对于某些种类的寄生虫，年龄增长、农村环境、与猫接触、食用未清洗的水果/蔬菜以及饮用未经核实来源的水与血清阳性显著相关。本研究为罗马尼亚食源性人畜共患寄生虫的流行病学现状提供了新的见解，强调需要提高人们对水、卫生设施和饮食习惯与这种被忽视的病理学之间关系重要性的认识。
