Lin Frank, Obeid Ayah, Bhalala Harsh, Patel Nishit, Ge Li, Modi Ronak
Internal Medicine, St. Luke's University Health Network, Bethlehem, PA.
ACG Case Rep J. 2024 Aug 30;11(9):e01455. doi: 10.14309/crj.0000000000001455. eCollection 2024 Sep.
Kikuchi-Fujimoto disease (KFD) is a rare and self-limiting disorder characterized by cervical lymphadenopathy and fever. In this report, we present a case of a 24-year-old man with known history of KFD who presented with lower gastrointestinal bleeding and acute blood loss anemia. Further evaluation with colonoscopy showed widespread ulcerations in the colon and terminal ileum with suspicion for Behcet's disease. Biopsy from the colonic mucosa and ileocecal valve demonstrated focal ulcer with cryptitis and lymphoid aggregates that can be seen in Behcet's syndrome; however, it lacks specificity and Behcet's disease is a clinical diagnosis. This case emphasizes the importance of including gastrointestinal bleeding as a potential manifestation due to Behcet's disease in patients diagnosed with KFD.
菊池-藤本病（KFD）是一种罕见的自限性疾病，其特征为颈部淋巴结病和发热。在本报告中，我们呈现了一例24岁男性病例，该患者有菊池-藤本病病史，此次出现下消化道出血和急性失血性贫血。结肠镜进一步检查显示结肠和回肠末端广泛溃疡，怀疑为白塞病。结肠黏膜和回盲瓣活检显示局灶性溃疡伴隐窝炎和淋巴样聚集，这在白塞综合征中可见；然而，其缺乏特异性，白塞病是一种临床诊断。该病例强调了在诊断为菊池-藤本病的患者中，将胃肠道出血作为白塞病潜在表现之一的重要性。
