Zheng Cheng, Qian Mengyi, Huang Tongmin, Liu Xingchen, Zeng Xiangman, Chen Xiaotong, Shen Yan, Chen Ping, Wu Feng, Gu Lihu
Department of General Surgery, Ningbo No. 2 Hospital, Ningbo, China.
The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.
Clin Med Insights Oncol. 2024 Sep 3;18:11795549241272654. doi: 10.1177/11795549241272654. eCollection 2024.
Patients with gastric cancer (GC) who underwent radical surgery require long-term follow-up (usually 5 years). The purpose of this study was to explore individualized follow-up strategies for patients with GC.
This is a retrospective cohort study that established a clinicopathologic database of patients who underwent gastrectomy from January 2010 to December 2020 at Ningbo No. 2 Hospital. Follow-up was performed until March 2023. The rate of new-onset recurrence of patients with GC was explored annually according to different pTNM stages, defining a recurrence rate of less than 1% as adequate follow-up time.
Of the 1606 patients who were eligible, the total number of patients who completed the 5- and 10-year follow-up was 1107 and 586, respectively. A total of 444 cases were diagnosed with recurrence. The recurrence rate for stage IA patients was consistently less than 1% during the follow-up time. The adequate follow-up time (the rate of new-onset recurrence less than 1%) was 5 years for stage IB and IIA patients, and 8 years for stage IIB and IIIA patients, respectively. In contrast, stage IIIB patients were always at risk of recurrence during the follow-up time (>1%). Time to a new recurrence rate for stage IIIC patients was 6 years.
Among patients who underwent radical gastrectomy, the rate of new-onset recurrence varied among patients with different pTNM stages. This study suggests that the follow-up of GC can be individualized and refer to pTNM stage.
接受根治性手术的胃癌（GC）患者需要长期随访（通常为5年）。本研究的目的是探索GC患者的个体化随访策略。
这是一项回顾性队列研究，建立了2010年1月至2020年12月在宁波市第二医院接受胃切除术患者的临床病理数据库。随访至2023年3月。根据不同的pTNM分期，每年探索GC患者的新发复发率，将复发率低于1%定义为足够的随访时间。
在1606例符合条件的患者中，完成5年和10年随访的患者总数分别为1107例和586例。共诊断出444例复发。IA期患者在随访期间的复发率始终低于1%。IB期和IIA期患者的足够随访时间（新发复发率低于1%）分别为5年，IIB期和IIIA期患者为8年。相比之下，IIIB期患者在随访期间始终有复发风险（>1%）。IIIC期患者达到新发复发率的时间为6年。
在接受根治性胃切除术的患者中，不同pTNM分期患者的新发复发率各不相同。本研究表明，GC的随访可以个体化，并参考pTNM分期。
