Balog Vera, Liszkay Gabor, Lantos Lajos, Jermendy Agnes, Belteki Gusztav
Neonatal Emergency & Transport Services of the Peter Cerny Foundation, Budapest, Hungary.
Division of Neonatology, Pediatric Center, MTA Center of Excellence, Semmelweis University, Budapest, Hungary.
J Perinatol. 2025 Jan;45(1):43-49. doi: 10.1038/s41372-024-02109-9. Epub 2024 Sep 6.
To analyse deviation of ventilator parameters from their set targets during high-frequency oscillatory ventilation (HFOV) with or without volume guarantee (VG) and compare the two modes during emergency neonatal transport.
Retrospective observational study using the fabian™ HFOi ventilator.
Median deviation of mean airway pressure from the set value was <1 cmHO. During HFOV the pressure amplitude differed from the set value by <1 cmHO. During HFOV-VG median deviation of the oscillation volume (VThf) from the targeted value was -0.07 mL/kg, but in some cases VThf was by >0.38 mL/kg below target. Setting maximum allowed amplitude 10 cmHO above the usually required amplitude improved maintenance of VThf. HFOV and HFOV-VG parameters were similar, except the lower amplitude during HFOV without VG. VThf <2.5 mL/kg avoided hypercapnia in most cases.
HFOV and HFOV-VG maintain ventilator parameters close to their targets and are promising modalities during neonatal transport.
分析在有或没有容量保证（VG）的高频振荡通气（HFOV）期间呼吸机参数与其设定目标的偏差，并在新生儿紧急转运期间比较这两种模式。
使用fabian™ HFOi呼吸机进行回顾性观察研究。
平均气道压与设定值的中位数偏差<1 cmH₂O。在HFOV期间，压力振幅与设定值的差异<1 cmH₂O。在HFOV-VG期间，振荡容积（VThf）与目标值的中位数偏差为-0.07 mL/kg，但在某些情况下，VThf比目标值低>0.38 mL/kg。将最大允许振幅设置为比通常所需振幅高10 cmH₂O可改善VThf的维持。HFOV和HFOV-VG参数相似，但无VG的HFOV期间振幅较低。在大多数情况下，VThf<2.5 mL/kg可避免高碳酸血症。
HFOV和HFOV-VG可使呼吸机参数维持在接近目标值的水平，是新生儿转运期间有前景的通气模式。
