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胶质母细胞瘤:治疗概述及磁共振波谱分析

Glioblastoma: Overview and Magnetic Resonance Spectroscopy Analysis for Treatment.

作者信息

Syed Waseem, Ibatullin Murat

机构信息

Medical Imaging, Lake Erie College of Osteopathic Medicine, Bradenton, USA.

出版信息

Cureus. 2024 Aug 7;16(8):e66390. doi: 10.7759/cureus.66390. eCollection 2024 Aug.

Abstract

Glioblastoma multiforme (GBM) is a very aggressive and fast-growing cancer of the brain that has a low life expectancy. Many new cases are diagnosed every year with each having a very poor prognosis. It is therefore of utmost concern to develop cures for such a devastating condition. Magnetic resonance spectroscopy details certain peaks that are of interest. In particular, later-stage astrocytomas exhibit prominent choline and creatine peaks. The creatine peak is known to enhance glioblastoma survival.

摘要

多形性胶质母细胞瘤(GBM)是一种极具侵袭性且生长迅速的脑癌,患者预期寿命较短。每年都有许多新病例被诊断出来,每个病例的预后都非常差。因此,研发针对这种毁灭性疾病的治疗方法至关重要。磁共振波谱详细显示了某些感兴趣的峰。特别是,晚期星形细胞瘤表现出明显的胆碱和肌酸峰。已知肌酸峰可提高胶质母细胞瘤的生存率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fbe6/11379102/79ea76a48352/cureus-0016-00000066390-i01.jpg

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