Laboratoire de Biologie Moléculaire et Cellulaire, Université des Sciences et Techniques de Masuku, Franceville, Gabon.
Centre Hospitalier Universitaire Amissa Bongo, Franceville, Gabon.
Pan Afr Med J. 2024 Apr 29;47:218. doi: 10.11604/pamj.2024.47.218.40737. eCollection 2024.
birth weight is a critical indicator of neonatal health and predicts future developmental outcomes. Despite its importance, there is a notable lack of research on the determinants of low birth weight (LBW) in southeast Gabon. This study aims to fill this gap by identifying factors contributing to LBW at the Centre Hospitalier Universitaire Amissa Bongo in Franceville.
this retrospective analysis covered the period from February 2011 to May 2017, focusing on postpartum women and their infants. Data were analyzed using R software (version 4.3.2), employing both descriptive statistics and logistic regression. Statistical significance was determined at a p-value of less than 0.05.
among the 877 births analyzed, the prevalence of LBW was 8.4%. Bivariate analysis identified several factors associated with an increased risk of LBW, including, primigravida women (COR (95%CI) =0.59 (0.36-0.98), P = 0.036), primiparous women (COR (95%CI) =0.58 (0.36-0. 94), P = 0.024), women with a gestational age <37 weeks (COR (95%CI) =0.07 (0.04-0.11), P<0.001), women with ≤2 antenatal visits (COR (95%CI) =0.39 (0.18-0.93), P= 0.021), and women who underwent cesarean delivery (COR (95%CI) =0.46 (0.26-0.84), P = 0.008). However, multivariate analysis showed that only gestational age (AOR (95%CI) = 0.07 (0.04-0.11), P<0.001) and cesarean delivery (AOR (95%CI) = 0.48 (0.25-0.95), P = 0.03) were significantly associated with LBW.
this study highlights the importance of gestational age and delivery method in the prevalence of LBW in southeast Gabon. These findings underscore the need for targeted interventions to address these risk factors, thereby improving neonatal health outcomes.
出生体重是新生儿健康的关键指标,可预测未来的发育结果。尽管其重要性不言而喻,但在加蓬东南部,关于低出生体重(LBW)决定因素的研究仍明显不足。本研究旨在通过确定法国城中心医院(Centre Hospitalier Universitaire Amissa Bongo)产妇及其婴儿 LBW 的相关因素来填补这一空白。
本回顾性分析涵盖了 2011 年 2 月至 2017 年 5 月期间的数据,重点关注产后妇女及其婴儿。使用 R 软件(版本 4.3.2)进行数据分析,采用描述性统计和逻辑回归。统计显著性水平定义为 p 值小于 0.05。
在分析的 877 例分娩中,LBW 的患病率为 8.4%。 单变量分析确定了一些与 LBW 风险增加相关的因素,包括初产妇(COR(95%CI)=0.59(0.36-0.98),P=0.036)、初产妇(COR(95%CI)=0.58(0.36-0.94),P=0.024)、 孕周<37 周的产妇(COR(95%CI)=0.07(0.04-0.11),P<0.001)、 产前检查次数≤2 次的产妇(COR(95%CI)=0.39(0.18-0.93),P=0.021)和接受剖宫产的产妇(COR(95%CI)=0.46(0.26-0.84),P=0.008)。然而,多变量分析显示,只有孕周(AOR(95%CI)=0.07(0.04-0.11),P<0.001)和剖宫产(AOR(95%CI)=0.48(0.25-0.95),P=0.03)与 LBW 显著相关。
本研究强调了加蓬东南部妊娠期和分娩方式在 LBW 发生率中的重要性。这些发现强调需要针对这些危险因素采取有针对性的干预措施,从而改善新生儿健康结局。