谷胱甘肽转移酶在神经元中FUS和TAF15相分离中的作用。 - Suppr

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超能文献

Role of glutathione transferase in phase separation of FUS and TAF15 in neurons.

作者信息

Kim Kiyoung

机构信息

Department of Medical Science, Soonchunhyang University, Asan, Korea.

出版信息

Neural Regen Res. 2025 Jul 1;20(7):1999-2000. doi: 10.4103/NRR.NRR-D-24-00409. Epub 2024 Jul 29.

DOI:10.4103/NRR.NRR-D-24-00409

PMID:39254557

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11691470/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b320/11691470/3d12368fdf6c/NRR-20-1999-g001.jpg

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本文引用的文献

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Nature. 2024 Jan;625(7994):345-351. doi: 10.1038/s41586-023-06801-2. Epub 2023 Dec 6.

Glutathionylation on RNA-binding proteins: a regulator of liquid‒liquid phase separation in the pathogenesis of amyotrophic lateral sclerosis.

Exp Mol Med. 2023 Apr;55(4):735-744. doi: 10.1038/s12276-023-00978-2. Epub 2023 Apr 3.

Reduced oxidative stress suppresses neurotoxicity in the Drosophila model of TAF15-associated proteinopathies.

Mol Brain. 2022 Nov 21;15(1):93. doi: 10.1186/s13041-022-00979-8.

Therapeutic modulation of GSTO activity rescues FUS-associated neurotoxicity via deglutathionylation in ALS disease models.

Dev Cell. 2022 Mar 28;57(6):783-798.e8. doi: 10.1016/j.devcel.2022.02.022. Epub 2022 Mar 22.

RNA modulates physiological and neuropathological protein phase transitions.

Neuron. 2021 Sep 1;109(17):2663-2681. doi: 10.1016/j.neuron.2021.06.023. Epub 2021 Jul 22.

Glutathione S-Transferase Rescues Motor Neuronal Toxicity in Fly Model of Amyotrophic Lateral Sclerosis.

Antioxidants (Basel). 2020 Jul 14;9(7):615. doi: 10.3390/antiox9070615.

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