Roby Brianne B, Schnell Avery, Johnson Tara L, Scholes Melissa, Scott Andrew R
Children's Minnesota, Department of Otolaryngology, 347 N. Smith Ave, Gardenview Suite 600, St Paul, MN, 55102, USA.
Tufts University School of Medicine, 145 Harrison Ave, Boston, MA, 02111, USA.
J Craniomaxillofac Surg. 2024 Dec;52(12):1449-1452. doi: 10.1016/j.jcms.2024.08.023. Epub 2024 Aug 28.
The goal of this study was to investigate the relationship between mandibular distraction osteogenesis (MDO) and rates of postoperative gastrostomy tube (G-tube) placement among patients with isolated and syndromic Robin sequence (RS). This study was a multi-institutional retrospective chart review of patients with RS who underwent MDO at one of three different pediatric tertiary medical centers. The primary aim of the study was to compare rates of G-tube placement following MDO among the three institutions. The primary outcome was analyzed using Fischer's exact test. The secondary aim of the study was to assess for other contributing factors to G-tube placement such as demographic differences, length of hospital stay, and age at MDO. Analysis of secondary outcomes was assessed using multiple logistic regression models. A total of 125 patients met the inclusion criteria, which required RS diagnosis, completion of MDO between 2004 and 2019, and adequate medical record availability. Sixty percent (n = 75) of subjects were categorized as isolated RS (iRS) and forty percent (n = 50) as syndromic RS (sRS). After MDO, 20% (n = 25) of all patients had G-tubes placed. Of the iRS group, 14.7% (n = 11) required a G-tube, while 28% (n = 14) of the sRS group required a G-tube. The post-operative G-tube rate was similar between institutions when considering all patients. When considering only those patients with iRS, the post-MDO G-tube rate at one center was significantly higher than the other two. Overall, most patients with RS did not require a G-tube after MDO, regardless of diagnosis. However, the significant differences in rates of G-tube placement among patients with iRS may indicate differing practice philosophies, surgical protocols, thresholds for G-tube placement, or regional influences between institutions.
本研究的目的是调查孤立性和综合征性罗宾序列征(RS)患者下颌骨牵张成骨术(MDO)与术后胃造瘘管(G管)置入率之间的关系。本研究是一项多机构回顾性图表审查,研究对象为在三个不同的儿科三级医疗中心之一接受MDO的RS患者。该研究的主要目的是比较三个机构中MDO术后G管置入率。使用费舍尔精确检验分析主要结局。该研究的次要目的是评估其他导致G管置入的因素,如人口统计学差异、住院时间和MDO时的年龄。使用多元逻辑回归模型评估次要结局分析。共有125名患者符合纳入标准,这要求确诊为RS、在2004年至2019年期间完成MDO且有足够的病历资料。60%(n = 75)的受试者被归类为孤立性RS(iRS),40%(n = 50)为综合征性RS(sRS)。MDO术后,所有患者中有20%(n = 25)置入了G管。在iRS组中,14.7%(n = 11)需要置入G管,而sRS组中有28%(n = 14)需要置入G管。考虑所有患者时,各机构之间术后G管置入率相似。仅考虑那些iRS患者时,一个中心的MDO术后G管置入率显著高于其他两个中心。总体而言,无论诊断如何,大多数RS患者在MDO后不需要置入G管。然而,iRS患者中G管置入率的显著差异可能表明各机构之间存在不同的实践理念、手术方案、G管置入阈值或地区影响。