Department of Internal Medicine, National Medical Center 20 de Noviembre ISSSTEFelix Cuevas, 540, Del Valle, Benito Juárez, Mexico City, 03104, Mexico.
Department of Ophthalmology, Regional Hospital Lic. Adolfo López Mateos ISSSTE, Mexico City, Mexico.
Curr Heart Fail Rep. 2024 Dec;21(6):530-540. doi: 10.1007/s11897-024-00682-w. Epub 2024 Sep 17.
This review focuses on the association between RA and heart failure, highlighting the role of inflammation and the prevalence of heart failure with preserved ejection fraction (HFpEF) in this population.
The incidence of heart failure in RA patients is two to three times higher than in the general population, with inflammation playing a significant role independent of traditional cardiovascular risk factors. HFpEF accounts for about half of heart failure cases and is increasingly recognized in RA patients, although it remains underdiagnosed. Atypical presentations and non-specific symptoms further complicate diagnosis. Early control of inflammation has been shown to reduce the risk of heart failure development and progression, improving both morbidity and mortality outcomes. Rheumatoid arthritis (RA) is a systemic inflammatory disease affecting approximately 1% of the population, with cardiovascular disease being the leading cause of premature death in these patients.
本文重点探讨 RA 与心力衰竭之间的关联，强调炎症在这一人群中的作用以及射血分数保留型心力衰竭（HFpEF）的患病率。
RA 患者心力衰竭的发病率比普通人群高 2 至 3 倍，炎症的作用独立于传统心血管危险因素。HFpEF 占心力衰竭病例的一半左右，在 RA 患者中越来越受到重视，但仍存在漏诊。不典型表现和非特异性症状使诊断更加复杂。早期控制炎症已被证明可降低心力衰竭发生和进展的风险，改善发病率和死亡率结局。类风湿关节炎（RA）是一种影响约 1%人群的系统性炎症性疾病，心血管疾病是这些患者过早死亡的主要原因。
